Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
Mugadziri Wekutengesa Valsartan uye Hunoenderana Nepakati:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Chemical Name | Valsartan |
Mashoko anoreva zvakafanana | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
Nhamba yeCAS | 137862-53-4 |
Nhamba yeCAT | RF-API32 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C24H29N5O3 |
Molecular Weight | 435.52 |
Melting Point | 116.0~117.0℃ |
Kugadzikana | Hygroscopic |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Muchena kana Off-White Powder;Haina kunhuhwirira, Hygroscopic |
Identification | IR spectrum yemuenzaniso inofanana nereferensi yakajairwa spectrum |
Identification | Iyo nguva yekuchengetedza yepamusoro peak muchromatogram yeassay kugadzirira inoenderana neyakajairwa gadziriro, sezvakawanikwa muAssay. |
Solubility | Soluble muMethanol neEthanol, Inonyungudika Mushoma muEthylacetate, Inonyungudika Zvishoma muDichloromethane, Insoluble mumvura |
Kunyorova (KF) | ≤1.00% |
Absorbance (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Residue paIgnition | ≤0.10% |
Heavy Metals | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Zvinhu zvinoenderana (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Single Unknown Kusachena | ≤0.10% |
Zvose Zvisina Kuchena | ≤0.30% (Kusingabatanidzi D-Valsartan) |
Residual Solvents (GC) | |
Methanol | ≤3000ppm |
Ethyl Acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Kuchena / Analysis Method | > 99.0% (HPLC yakaverengerwa pane anhydrous, solvent-isina hwaro) |
Test Standard | United States Pharmacopoeia (USP) |
Usage | Active Pharmaceutical Ingredient (API) |
Valsartan (CAS: 137862-53-4) The Production Process Flow
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weValsartan (CAS: 137862-53-4) ine mhando yepamusoro.Valsartan is nonpeptide angiotensin II AT1 receptor antagonist, Antihypertensive, ine mukana wekukwira kweropa uye kutadza kutsvaga kwemoyo.
Valsartan's antihypertensive mhedzisiro yakasimba pane yeenalapril uye inokodzera kurapa hypertension, yakapfava kusvika pakati pekutanga hypertension, uye kunyanya yechipiri hypertension inokonzerwa nekukuvara kwerenal.Inogona kuderedza zvakanyanya proteinuria yevarwere vane hypertension vane chirwere cheshuga kana chiropa chakajairwa, uye inogona kukurudzira uric acid uye urinary sodium kuchengetedza itsvo.Valsartan yakakodzerawo kudzikisa kufa kwemoyo kune varwere vane njodzi yakanyanya (kutadza ventricular kana kusashanda zvakanaka) mushure mekusangana nechirwere chemoyo.