Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API High Quality
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Chemical Name | Vonoprazan Fumarate |
| Mashoko anoreva zvakafanana | TAK-438 |
| Nhamba yeCAS | 1260141-27-2;881681-01-2 |
| Nhamba yeCAT | RF-API99 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C21H20FN3O6S |
| Molecular Weight | 461.463 |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kana Inenge-Ichena Crystalline Powder |
| Kuzivikanwa 1 H-NMR | Zvinoenderana neStandard |
| Kuzivikanwa IR | Iyo IR Absorption spectrum yemuenzaniso concordant ine referensi chiyero |
| Kuzivikanwa HPLC | Nguva yekuchengeta yemuenzaniso concordant nereference standard |
| Mvura Yemukati | ≤0.50% |
| Residue paIgnition | ≤0.20% |
| Heavy Metals (as Pb) | ≤20ppm |
| Related Substances | |
| Kusachena A | ≤0.20% |
| Kusachena B | ≤0.15% |
| Kusachena C | ≤0.15% |
| Chero Kumwe Kusachena | ≤0.10% |
| Zvose Zvisina Kuchena | ≤1.0% |
| Residual Solvents | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl Acetate | ≤0.50% |
| Assay / Analysis Method | 98.0%~102.0% (NeHPLC) |
| Test Standard | Enterprise Standard |
| Usage | API |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, unyoro.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), proton pump inhibitor (PPI), ine simba uye inobata nemuromo potassium-competitive acid blocker (P-CAB), ine antisecretory. chiitiko.Vonoprazan Fumarate inhibits H+,K+-ATPase chiitiko mu porcine gastric microsomes ine IC50 ye 19 nM pa pH 6.5.Vonoprazan Fumarate (Takecab), yakawanikwa uye yakagadzirwa naTakeda naOtsuka, yakagamuchirwa nePMDA yeJapan muna December 2014. Vonoprazan Fumarate inonyanya kushandiswa pakurapa helicobacter pylori chirwere, gastroesophageal reflux, peptic ulcer, duodenal ulcer, esophagitis, gas. ulcer uye zvimwe zvirwere zvine chekuita negastric acid.Chigadzirwa chacho chine simba, risingaperi rekudzivirira kwegastric acid secretion.Pamushonga wekurapa, Vonoprazan Fumarate haina mhedzisiro pane mamwe ma enzymes uye diki mhedzisiro pamabasa emuviri emuviri.Yakachengeteka uye inoshiviririka.
