1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS 22224-41-5 daahirnimo
Dhexdhexaadiyeyaasha la xidhiidha sahayda ganacsiga ee Clofarabine:
Clofarabine CAS: 123318-82-1
2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose CAS: 97614-43-2
β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS: 6974-32-9
1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS: 22224-41-5
2,6-Dichloropurine CAS: 5451-40-1
Magaca Kiimikada | 1,3,5-Tri-O-benzoyl-D-Ribofuranose |
Lambarka CAS | 22224-41-5 |
Lambarka CAT | RF-PI223 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C26H22O8 |
Miisaanka Molecular | 462.45 |
Meesha dhalaalaysa | 125.0-129.0 ℃ ( shid) |
Solubility | Aan ku milmin Biyaha |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama Off-Cad |
daahirnimo | ≥99.0% |
Khasaare xagga qalajinta | ≤1.00% |
Xumaanta Keliga ah ee ugu badan | ≤0.50% |
Wadarta wasakhda | ≤1.00% |
Biraha culus | ≤20pm |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Clofarabine (CAS: 123318-82-1) |
Xidhmada: Dhalo, boorsada bireed aluminium, durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
1,3,5-Tri-O-benzoyl-D-Ribofuranose (CAS: 22224-41-5) waa qalab bilow ah oo loogu talagalay isku-dhafka nucleoside.Waxa loo isticmaali karaa sidii dhex dhexaadinta Clofarabine (CAS: 123318-82-1).Clofarabine waa daawo cusub oo purine nucleoside anticancer ayaa markii ugu horeysay si guul leh u soo saartay shirkadda Top10 biopharmaceutical ee Shirkadda United States-Genzyme oo leh magacyada ganacsiga "Clofarabine".Bishii Disembar 28, 2004 FDA waxay adeegsatay raad-raac degdeg ah si loo oggolaado Clofarabine si loogu codsado carruurta qaba leukemia ba'an oo soo noqnoqda ama soo noqnoqda.Clofarabine wuxuu isku daraa faa'iidooyinka Fludarabine iyo Cladribine si loo joojiyo labadaba DNA polymerase iyo RIbonucleic acid reductase.Hadda waa dawada kaliya ee ku haboon daaweynta leukemia carruurnimada.Daraasaduhu waxay caddeeyeen in waxtarkeeda daawaynta ay aad u sarreyso, iyo wadarta guud ee jawaabta bukaannada aan wax jawaab ah ka helin laba kiimoterabi caadiga ah waa 31%.Dulqaadka bukaanku waa wanaagsan yahay, ma jiro falcelin xun oo aan la saadaalin karin;Waxay leedahay astaamo liddi ku ah antitumor oo suurtagal ah.