2-(Chloromethyl) -4-Methylquinazoline CAS 109113-72-6 Linagliptin Nadiifinta Dhexdhexaadka ah ≥99.0% (HPLC)
Soo saaraha Linagliptin iyo Dhexdhexaadiyeyaasha la xidhiidha:
Linagliptin CAS 668270-12-0
Dhexdhexaadiyaha Nucleus Waalidka ee Linagliptin CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino) piperidine CAS 309956-78-3
(R)-(-)-3-Aminopperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0
Magaca Kiimikada | 2-(Chloromethyl) -4-Methylquinazoline |
La mid ah | Dhexdhexaadiyaha Linagliptin A |
Lambarka CAS | 109113-72-6 |
Lambarka CAT | RF-PI498 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C10H9ClN2 |
Miisaanka Molecular | 192.64 |
Cufnaanta | 1.251 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Jaalle cirro leh ilaa budada Brown cirro |
Aqoonsiga A | Muunada IR spectrum waa in ay la mid tahay heerka caadiga ah |
Aqoonsiga B | Waqtiga haynta ee mabda'a ugu sarreeya ee muunadku waa inuu u dhigmaa heerka caadiga ah |
Solubility | Ku milmay Methylene Chloride;Aan ku milmin Biyaha |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Meesha dhalaalaysa | 60.0 ilaa 65.0 ℃ |
Biyaha (KF) | ≤0.50% |
Hadhaaga dabka | ≤0.50% |
Walxaha laxidhiidha | |
Xumaanta Keliya | ≤0.30% |
Wadarta wasakhda | ≤1.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Linagliptin (CAS: 668270-12-0) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
2-(Chloromethyl) -4-Methylquinazoline (CAS: 109113-72-6) waxaa loo isticmaalaa dhexdhexaadinta diyaarinta Linagliptin (CAS: 668270-12-0), iyo wasakhdeeda.Linagliptin, oo lagu iibiyo magaca summadaha Tradjenta iyo kuwa kale, waa dawo loo isticmaalo daawaynta nooca 2-aad ee sonkorowga mellitus. Guud ahaan waa laga doorbidaa metformin iyo sulfonylureas sida daawaynta bilowga ah.Waxa si wadajir ah loo isticmaalaa jimicsi iyo cunto.Laguma talinayo nooca 1aad ee sonkorowga.Waxay ka shaqeysaa iyada oo kordhinaysa soosaarka insulinta waxayna yaraynaysaa wax soo saarka glucagon ee xameetida.Linagliptin waxaa loo oggolaaday isticmaalka caafimaadka gudaha Mareykanka 2011. Linagliptin waa mid aad u awood badan, doorasha dipeptidyl peptidase-4 (DPP-4) inhibitor leh IC50 of 1 nM.