2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Nadiifinta ≥99.0% Warshada Dhexe ee Pirfenidone
Soo-saarka wax-soo-saarka, Nadiifinta Sare, Wax-soo-saarka Ganacsiga
Magaca Kiimikada: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5
| Magaca Kiimikada | 2-Hydroxy-5-Methylpyridine |
| La mid ah | 5-Methyl-2(1H)-Pyridinone;2-Hydroxy-5-Picoline;6-Hydroxy-3-Picoline;5-Methyl-2-Pyridinol |
| Lambarka CAS | 1003-68-5 |
| Lambarka CAT | RF-PI549 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C6H7NO |
| Miisaanka Molecular | 109.13 |
| Meesha dhalaalaysa | 183.0 ilaa 187.0 ℃ ( shid) |
| Solubility | Ku milma Methanol |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Ka-bax-caddan ilaa budada crystalline jaalaha ah |
| daahirnimo | ≥99.0% |
| Waxyaabaha qoyaanka ah (KF) | ≤0.50% |
| Hadhaaga dabka | ≤0.50% |
| Xumaan Keli ah | ≤0.50% |
| Wadarta wasakhda | ≤1.00% |
| Xalalka Haraaga ah | |
| n-Butaanol | ≤0.30% |
| Ethanol | ≤0.30% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Pirfenidone (CAS: 53179-13-8) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) waxaa loo isticmaalaa sida dhexdhexaadka daawada ee Pirfenidone (CAS: 53179-13-8).Pirfenidone (PFD) waa nooc cusub oo ketones pyridine ah kaas oo leh saameyn ballaaran oo anti-fibrotic ah, awood u leh inuu ka hortago oo uu beddelo samaynta fibrosis iyo nabarrada.Waxay ka soo gashay suuqa Shionogi, Japan 2008dii waxaana oggolaaday Maamulka Cuntada iyo Dawooyinka ee Mareykanka.Waa daawadii ugu horreysay ee soo martay marxaladda III tijaabo caafimaad (oo ay ku jiraan ku-noqoshada, la kala soocay, iyo kantaroolka placebo) taasoo muujisay waxtarkeeda daawaynta idiopathic pulmonary fibrosis (IPF);Intaa waxaa dheer, daawadu waxay leedahay waxtarka wanaagsan ee daaweynta cudurrada fibrotic qaarkood sida fibrosis interstitial kelyaha iyo fibrosis beerka.
