2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Warshada Dhexe ee Tayada Sare
Soo-saarka wax-soo-saarka, Tayada Sare, Wax-soo-saarka Ganacsiga
Tolvaptan iyo Dhexdhexaadiyayaasha la xidhiidha:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Magaca Kiimikada | 2-Methyl-4-Nitrobenzoic acid |
La mid ah | 4-Nitro-o-Toluic Acid;4-Nitro-2-Methylbenzoic Acid |
Lambarka CAS | 1975-51-5 |
Lambarka CAT | RF-PI397 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C8H7NO4 |
Miisaanka Molecular | 181.15 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Ku dhawaad Caddaan ama budo jaale ah oo cirro leh |
1H-NMR | Waafaqsan Qaab-dhismeedka |
Daahirnimada / Habka Falanqaynta | ≥98.0% (HPLC) |
Meesha dhalaalaysa | 153.0 ~ 156.0 ℃ |
Qoyaanka (KF) | ≤0.50% |
Hadhaaga dabka | ≤0.50% |
Wadarta wasakhda | ≤2.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Tolvaptan (CAS 150683-30-0) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) waxaa loo istcimaalaa dhex-dhexaadka dawooyinkaTolvaptan waa doorasho, tartan arginine vasopressin receptor 2 antagonist leh IC50 ee 1.28μM ee ka hortagga isku-darka platelet-ka ee AVP.Tolvaptan waxaa loo isticmaalaa in lagu daweeyo hyponatremia (heerka soodhiyamka dhiigga oo hooseeya) ee la xidhiidha wadne-gabka wadnaha, cirrhosis, iyo cilladda hormoonka antidiuretic ee aan habboonayn (SIADH).Tolvaptan waxaa ansixiyay Maamulka Cuntada iyo Dawooyinka ee Maraykanka Maajo 19, 2009, waxaana iibisa Otsuka Pharmaceutical Co. oo hoos timaada magaca ganacsiga Samsca.