2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Nadiif Dhexdhexaad ah>99.0% (GC)
Soo saaraha iyo alaab-qeybiyaha hormuudka ah, Dhexdhexaadiyeyaasha Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
Magaca Kiimikada | 2,3-Dihydrobenzofuran |
La mid ah | Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo[b]furan;2,3-Dihydro-1-Benzofuran |
Lambarka CAS | 496-16-2 |
Lambarka CAT | RF2884 |
Heerka Saamiyada | Kaydka dhexdiisa, Awood Wax-soo-saar 20 Tan bishii |
Qaanuunka molecular | C8H8O |
Miisaanka Molecular | 120.15 |
Meesha dhalaalaysa | -21℃ |
Barta Karsan | 188.0 ~ 189.0 ℃ ( shidan) |
Barta Fiishka | 66℃ |
Solubility | Khamriga: milma |
Xusuusin Khatarta | Xanaaqsan |
TSCA | Haa |
Koodhka HS | 29329995 |
Heerkulka Kaydinta | Lagu xidhay qalalan, heerkulka qolka |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Dareere aan Midab lahayn ama Jaalle ah oo Cad |
Daahirnimada / Habka Falanqaynta | >99.0% (GC) |
Biyaha (waxaa qoray Karl Fischer) | <0.50% |
Cufnaanta (20 ℃) | 1.065 ~ 1.085 |
Tusmada N20/D | 1.547 ~ 1.551 |
Xumaanta Keliya | <0.50% |
Wadarta wasakhda | <1.00% |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Dawada ee Ramelteon (CAS: 196597-26-9) |
Xidhmada: Dhalada fluorinated, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
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Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
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2,3-Dihydrobenzofuran (CAS: 496-16-2) ayaa si weyn loogu isticmaalaa isku-dhafka xayndaabyada tricyclic iyo sidoo kale waa qalab dhexdhexaad ah oo dhexdhexaad ah oo loogu talagalay isku-darka daawooyinka muhiimka ah.2,3-Dihydrobenzofuran waxaa loo isticmaali karaa dhexdhexaadinta Ramelteon (CAS: 196597-26-9).Ramelteon, oo ay u suuq geysay Rozerem by Takeda Pharmaceuticals North America, waa wakiilka hurdada kaas oo si xushmad leh ugu xidha MT1 iyo MT2 reseptors ee nukleus suprachiasmatic (SCN), halkii ay ku xidhi lahaayeen reseptors GABAA, sida daawooyinka sida zolpidem.Si kastaba ha ahaatee uma muuqato in ay dedejinayso bilawga hurdada ama inta hurdo ee qofku helo.Waxaa oggolaaday Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA) si loogu isticmaalo muddada dheer.Ramelteon ma tusin wax la mahadin karo oo ku xidhan soo-qabayaasha GABAA, kuwaas oo la xidhiidha anxiolytic, myorelaxant, iyo saamaynta amnesic.Si ka duwan inta badan daawaynta hurdo la'aanta ee bartilmaameedka ah GABA (g-aminobutyric acid) isku xidhka reseptor-ka, ramelteon waa agonist ee reseptor-ka melatonin.Gaar ahaan, waxay leedahay xulasho sare oo loogu talagalay noocyada MT1 iyo MT2, kuwaas oo lagu lug yeeshay dayactirka laxanka wareegga, oo ka sarreeya soo-dhoweeyaha MT3 ee mas'uul ka ah hawlaha kale ee melatonin.2,3-Dihydrobenzofuran ayaa sidoo kale loo isticmaalaa isku-dhafka wakiilada antitumor benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, iwm.