2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Dhexdhexaadiyaha COVID-19

Sharaxaad Gaaban:

Magaca: 2,3,5-Tri-O-benzyl-D-ribonolactone

La mid ah: 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone

CAS: 55094-52-5

Muuqashada: Caddaan ilaa ku dhawaad cad budo

Daahirsanaanta: ≥99.0%

Dhexdhexaadiyaha Remdesivir (CAS 1809249-37-3) COVID-19

Tayada Sare, Wax Soo Saarka Ganacsiga

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Sharaxaad:

Soo-saare Ganacsi Supply Remdesivir iyo Dhexdhexaadiyayaasha La Xiriira ee Tayada Sare leh
Remdesivir CAS 1809249-37-3
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Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
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Guryaha Kiimikada:

Magaca Kiimikada	2,3,5-Tri-O-benzyl-D-ribonolactone
La mid ah	2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Intermediate
Lambarka CAS	55094-52-5
Lambarka CAT	RF-PI301
Heerka Saamiyada	Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram
Qaanuunka molecular	C26H26O5
Miisaanka Molecular	418.49
Meesha dhalaalaysa	54.0-55.0 ℃
Xaalada Kaydinta	Heerkulka qolka
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Yellow ama Cad Adag
Solubility	Ku milmay CH2Cl2 oo aan lagu milmi karin H2O
NMR iyo MS	Waa in uu u hogaansamo
Aqoonsiga	IR iyo TLC
Qoyaanka	≤1.0%
Hadhaaga dabka	≤0.50%
Xumaan Shaqsiyeed Kasta	≤0.50%
Biraha culus	≤50pm
HPLC (210nm)	≥99.0%
HPLC (ELSD)	≥99.0%
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadiyaha Remdesivir (CAS 1809249-37-3)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

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FAQ:

Codsiga:

2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) waa dhexdhexaadiye Remdesivir.Remdesivir (CAS 1809249-37-3) waa dawo cusub oo ka hortag fayrus ah oo ku jirta fasalka analogs nucleotide, oo loo isticmaalo daawaynta COVID-19.Remdesivir (GS-5734) waa analog cusub oo ka hortagta fayraska nucleoside kaas oo ka hortagaya fayraska cagaarshow murine (MHV) oo la mid ah EC50 sida SARS-CoV iyo MERS-CoV.Coronaviruses (CoVs) waa dareen togan, fayrasyo RNA ah oo hal-xidhaale leh oo saameeya tiro balaadhan oo ah martigaliyayaasha xayawaanka.Bini'aadamka, CoVs waxaa loo aqoonsaday inay caadi ahaan sababaan hargab iyo oof-wareen ilaa ay ka soo baxayaan cudurka daran ee neef-mareenka ee coronavirus (SARS-CoV) 2002 iyo Bariga Dhexe ee neef-mareenka cudurka coronavirus (MERS-CoV) ee 2012 laga soo xigtay ilo zoonotic ah.Remdesivir waa daawada monophosphoramidate ee C-adenosine nucleoside analogue GS-441524.Unugyada buro maskaxda ee daahday (DBT) ee uu ku dhacay MHV, GS-5734 waxay xakamaysay MHV si ka xoog badan GS-441524, oo leh GS-5734 EC50 ee 0.03 M. Intaa waxaa dheer, EC50 qiyamka ayaa la go'aamiyay ka dib daaweynta GS-441524 iyo GS-5734 ee SARS-CoV- iyo MERS-CoV-ku-dhacey dhaqamada unugga hawo-mareenka aasaasiga ah ee bini'aadamka (HAE).