2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 daahirnimo ≥99.5% (GC) Sitagliptin Fosfate Monohydrate Dhexdhexaad
Bixinta Sitagliptin Phosphate Monohydrate Dhexdhexaadiyaha La Xiriira:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Fosfate Monohydrate Dhexdhexaad CAS 486460-21-3
| Magaca Kiimikada | 2,4,5-Trifluorophenylacetic acid |
| Lambarka CAS | 209995-38-0 |
| Lambarka CAT | RF-PI1191 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C8H5F3O2 |
| Miisaanka Molecular | 190.12 |
| Meesha dhalaalaysa | 121.0 ilaa 125.0 ℃ |
| Solubility | Ku milma Methanol |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ilaa budo cad-cad |
| Daahirnimada / Habka Falanqaynta | ≥99.5% (GC) |
| Qoyaanka (KF) | ≤0.50% |
| Hadhaaga Igniton | ≤0.50% |
| Wadarta wasakhda | ≤0.50% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Sitagliptin Fosfate Monohydrate (CAS: 654671-77-9) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) waa dhexe ee Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) waxaa loo isticmaalaa daawaynta DM nooca 2 sababtoo ah waxay wanaajisaa xakamaynta glycemic iyadoo kordhinaysa heerarka hormoonnada incretin ee firfircoon, GLP-1 (peptide-1) iyo GIP (glucose-based insulinotropic peptide).Dhaqdhaqaaqa incretins ee unugyada β-pancreatic waxay sababtaa heerarka korodhka adenosine monophosphate (cAMP) iyo calcium intracellular, oo leh dheecaanka insulin-ku-tiirsanaanta gulukooska ee xiga (2).Daawadan hypoglycemic waxaa iska leh fasalka cusub ee loo yaqaan 'dipeptidyl peptidase IV inhibitors'.STG waxaa ansixiyay FDA 2006.
