(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 Atazanavir Dhexdhexaad Sare Nadiifnimo
Soo saaraha soo saaraha Atazanavir Dhexdhexaadiyeyaasha la xidhiidha
Moc-L-Tert-Leucine CAS 162537-11-3
4- (2-Pyridyl) benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
Tayada Sare, Wax Soo Saarka Ganacsiga
Magaca Kiimikada | (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
La mid ah | (2R,3S)-3-(tert-Boc) amino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(tert-Butoxycarbonyl) amino-1,2-epoxy-4-phenylbutane;Atazanavir Intermediate;Atazanavir wasakh C;threo-N-Boc-L-phenylalanine epoxide |
Lambarka CAS | 98760-08-8 |
Lambarka CAT | RF-PI288 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C15H21NO3 |
Miisaanka Molecular | 263.34 |
Xaalada Maraakiibta | Heerkulka deegaanka hoostiisa |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Crystalline ee Cadaan iyo Off-White |
Aqoonsiga | Aqoonsiga waxaa xaqiijiyay HPLC RT |
Solubility | Ku milma Methanol |
Wareeg gaar ah | -10°~ -20° |
Biyaha (KF) | ≤0.50% |
Hadhaaga dabka | ≤0.20% |
Walxaha laxidhiidha | |
Xumaan (RRT0.97) | ≤0.30% |
Xumaan Keli ah | ≤0.30% |
Wadarta wasakhda | ≤1.0% |
Biraha culus | ≤20pm |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Nadiifinta Enantiomeric | ≤0.30% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor |
Xidhmada: Dhalo, Bac aluminium biil ah, Durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya iyo alaab-qeybiyaha (2R,3S) -1,2-Epoxy-3-(Boc-Amino) -4-Phenylbutane (CAS 98760-08-8) oo leh tayo sare leh, dhexdhexaad ah Atazanavir (CAS 198904-31-3) iyo Atazanavir Sulfate (CAS 229975-97-7).Atazanavir waa novel azapeptide HIV protease inhibitor (PI).
Atazanavir waa horjoogaha fayraska difaaca jirka ee nooca 1 (HIV-1) protease, oo ah enzyme lagama maarmaan u ah ka-hortagga Gag iyo Gag-Pol polyproteins ee borotiinnada qaabdhismeedka iyo enzymatic ee looga baahan yahay fayraska.Waxa ay leedahay farmacophore motif la mid ah lixda kale ee si weyn loo suuqgeeyay ee HIV protease inhibitors, kuwaas oo intooda badan ku salaysan qaab-dhismeedka hydroxyethylamine.Si gaar ah, waxa ay leedahay ujeedo aza-peptide ah laakiin waxa ay ilaalisaa xubno badan oo farmashiye ah oo la mid ah oo ay ku jiraan qaybo lipophilic ah oo loo malaynayo inay ku xidhan yihiin boosaska S2, S1, S′1, iyo S′2.