(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Darunavir Dhexdhexaad Sare Nadiifnimo
Soo saaraha soo saaraha Darunavir Alaabta la xidhiidha:
Daunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Magaca Kiimikada | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
| La mid ah | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino) -1,2-epoxy-4-phenylbutane;Darunavir Intermediate |
| Lambarka CAS | 98737-29-2 |
| Lambarka CAT | RF-PI286 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C15H21NO3 |
| Miisaanka Molecular | 263.33 |
| Solubility | Aan ku milmin Biyaha.Ku milmay Methanol, Chloroform |
| Xaalada Maraakiibta | Lagu soo raray Heer kulka jawiga |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystalline ee Caddaan iyo Off-White |
| Aqoonsiga (HPLC) | Aqoonsiga waxaa xaqiijiyay HPLC |
| Meesha dhalaalaysa | 123.0 ~ 128.0 ℃ |
| Qoyaanka (KF) | ≤0.50% |
| Hadhaaga dabka | ≤0.20% |
| Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
| Chlorohydrin (HPLC) | ≤0.20% |
| Chloromethyl Ketone | ≤0.10% |
| Xumaanta Keliga ah ee Kale | ≤0.20% |
| Wadarta wasakhda | ≤1.0% |
| Xumaanta Chiral | ≤0.30% |
| Biraha culus | ≤20pm |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Xidhmada: Dhalo, Bac aluminium biil ah, Durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Shanghai Ruifu Chemical Co., Ltd. waa hormuudka soo saaraha iyo alaab-qeybiyaha (2S,3S) -1,2-Epoxy-3-(Boc-Amino) -4-Phenylbutane (CAS: 98737-29-2) oo leh tayo sare leh , dhexdhexaad ah sida caadiga ah ee isku dhafka Darunavir (CAS 206361-99-1) iyo Darunavir Ethanolate (CAS 635728-49-3).
Darunavir (CAS 206361-99-1) waa nooc cusub oo aan peptide-ka-hortagga dib-u-celinta protease-ka ee daawaynta AIDS-ka.Waxaa markii ugu horreysay soo saartay laanta dawooyinka Johnson ee Iceland, Tibotec.Waxay ka mid tahay bioavailability-ga ugu sarreeya ee 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir iyo ABT378/r).Waxay u shaqaysaa iyada oo xannibaysa samaynta qaybo cusub oo baaluq ah oo ka yimaadda dusha unugyada martida loo yahay oo ay joojiso borotiinka fayraska.Marka badeecada la isticmaalo muddo dheer, waxay caadi ahaan hoos u dhigi kartaa fayraska HIV-ga ee dhiigga, kordhinta tirada unugyada CD4, waxay yareysaa fursada infekshanka HIV, waxay wanaajisaa tayada nolosha waxayna kordhisaa nolosha.Waxay ku habboon tahay dadka qaangaarka ah ee uu ku dhacay fayraska HIV laakiin aan wax saameyn ah ku yeelan isticmaalka dawooyinka lidka ku ah antiretroviral ee jira.Daawada waa in lagu daraa isticmaalka qiyaas yar oo ritonavir ah ama wakiilada kale ee ka hortagga retroviral, si loo hagaajiyo waxtarka.
