3α-Hydroxy-7-oxo-5β-Cholanic Acid CAS 4651-67-6 daahirnimo>99.5% (HPLC)
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Magaca Kiimikada | 3α-Hydroxy-7-oxo-5β-Cholanic Acid |
La mid ah | 3α-Hydroxy-7-keto-5β-Cholanic acid;3alpha-Hydroxy-7-oxo-5beta-Cholanic acid;7-Ketolithocholic acid;Ursodeoxycholic acid EP wasakh F |
Lambarka CAS | 4651-67-6 |
Lambarka CAT | RF-PI1988 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C24H38O4 |
Miisaanka Molecular | 390.56 |
Cufnaanta | 1.124 ± 0.060 g / cm3 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa cad-cad budo ama budo;Ma jiro walxo shisheeye, ma jiro ur cad |
Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) |
Meesha dhalaalaysa | 201.0 ~ 205.0 ℃ |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.20% |
Walxaha laxidhiidha | |
Xumaanta Keliya | <0.50% |
Wadarta wasakhda | <0.50% |
Biraha culus | ≤10pm |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Aashitada Obeticholic (CAS: 459789-99-2) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
3a-Hydroxy-7-oxo-5β-Cholanic Acid (CAS: 4651-67-6) waa dhexdhexaadiye Acid Acid (CAS: 459789-99-2).Obeticholic acid waxa kale oo loo yaqaan 6-Ethylchenodeoxycholic acid.Obeticholic acid waa soosaar cusub oo ah chenodeoxycholic acid (CDCA) ee asiidhyada asaasiga ah ee bile aadamiga, ligand dabiiciga ah ee farnesoid x reseptors (FXR).Obeticholic acid waxa soo saartay shirkad Maraykan ah oo dawooyinka samaysa ee Intercept oo ah dawadii ugu horaysay ee lagu daweeyo xanuunka beerka ee cholestatic muddo 20 sano ah, waxaana lagu maamulaa bukaanada aan si fiican uga jawaabin ama aan u adkaysan karin daawadii hore ee daawaynta ursodeoxycholic acid.Obeticholic acid ayaa sidoo kale la tijaabiyay si loo daweeyo nooc ka badan oo ah beerka dufanka leh - cudurka beerka dufanka leh ee aan alkoholka ahayn (NAFLD).Obeticolic acid sidoo kale waa la soo saari karaa si loo daaweeyo cudurrada kale ee beerka iyo xiidmaha.