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3-[3- (Trifluoromethyl) phenyl] -1-Propanol CAS 78573-45-2 Cinacalcet Hydrochloride daahirnimo dhexdhexaad ah>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee 3-[3- (Trifluoromethyl) phenyl] -1-Propanol (CAS: 78573-45-2) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, tiro yar iyo tiro badan oo la heli karo.Iibka 3-[3-(Trifluoromethyl) phenyl] -1-Propanol,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | 3-[3-(Trifluoromethyl) phenyl] -1-Propanol |
| La mid ah | 3-[3- (Trifluoromethyl) phenyl] propanol;3- (3'-Trifluoromethylphenyl) propanol;3- (3- (Trifluoromethyl) phenyl) propan-1-ol;3-(Trifluoromethyl) benzene propanol |
| wasakhnimo | Isku dhafka USP Cinacalcet La Xiriira E |
| Heerka Saamiyada | Suuqa dhexdiisa, Miisaanka Ganacsiga |
| Lambarka CAS | 78573-45-2 |
| Qaanuunka molecular | C10H11F3O |
| Miisaanka Molecular | 204.19 g/mol |
| Barta Karsan | 60℃/1.13mmHg( shid) |
| Barta Fiishka | 105℃ |
| Heerkulka Kaydinta | Qabow & Meel Qalalan |
| COA & MSDS | La heli karo |
| Qaybta | Dhexdhexaadiyeyaasha Daawooyinka |
| Summada | Kiimikada Ruifu |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Dareere Jaalle ah oo aan Midab lahayn | U hogaansama |
| Biyaha waxaa qoray Karl Fischer | <0.50% | 0.07% |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) | 99.60% |
| Tusmada N20/D | 1.462 ~ 1.466 | U hogaansama |
| Cufnaanta (20 ℃) | 1.212 ~ 1.216 | U hogaansama |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| 1 H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabta waa la tijaabiyay oo waafaqay qeexitaannada | |
| Codsiga | Dhexdhexaadiyaha Cinacalcet Hydrochloride (CAS: 364782-34-3) | |
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3-[3- (Trifluoromethyl) phenyl] -1-Propanol (CAS: 78573-45-2) waa dhexdhexaad ka mid ah isku dhafka Cinacalcet Hydrochloride (CAS: 364782-34-3).Cinacalcet waa gelitaanka ugu horreeya ee fasalka cusub ee wakiilada daweynta ee loo yaqaan calcimimetics.Waxaa loo bilaabay sidii daweyn afka ah oo loogu talagalay hyperparathyroidism secondary (SHPT) ee bukaanada qaba cudurka kelyaha ee joogtada ah ee sifeynta iyo hypercalcemia ee bukaanka qaba kansarka parathyroid.SHPT waxay la xiriirtaa kororka dheecaanka hormoonka parathyroid (PTH), kaas oo ay kiciso heerarka serum ee kaalshiyamka oo hooseeya taas oo ka dhalatay fashilka kelyaha si ay u nadiifiyaan fosfooraska jirka iyo awood la'aanta inay soo saaraan qadar ku filan oo fitamiin D ah. Cawaaqibka PTH ee kordhay. waxaa ka mid ah kicinta dhaqdhaqaaqa osteoclastic, dib u soo noqoshada lafaha kortikal iyo dhuuxa fibrosis.Dheecaanka PTH waxaa ugu horayn nidaamiya kaalshiyam-dareemaha receptor (CaR), kaas oo ku yaala dusha sare ee unugga sare ee qanjidhada parathyroid.Calcimimetics waxay ku xidhan tahay CaR waxayna kordhisaa dareenka CaR ee kaalshiyamka unugyada ka baxsan, taas oo awood u siinaysa firfircoonideeda heerarka aan caadiga ahayn ee kalsiyumka serum.Natiijo ahaan, joogitaanka wakiiladan, heerarka hoose ee calcium endogenous ee bukaanada qaba cillad kelyaha ayaa awood u leh inay saameyn ku yeeshaan dheecaanka PTH.Kansarka Parathyroid sidoo kale wuxuu la xiriiraa heerarka PTH ee sarreeya, kaas oo ay wadaan dhaqdhaqaaqa qanjidhada parathyroid oo madax-bannaan oo ka dibna keena hypercalcemia.Inkasta oo dib-u-soo-celinta qalliinku ay tahay daaweynta asaasiga ah ee lagu daweeyo hypercalcemia ee bukaannada kansarka qanjirka 'parathyroid', calcimimetics waxay bixisaa beddel aan qaliinka ahayn oo loogu talagalay bukaannada qaba parathyroidectomy-ka-fashilmay, kansarka qanjirka 'parathyroidectomy', ama khatarta qalliinka sare.
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