3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Dhexdhexaad Nadiifnimo>98.0% (HPLC)
Kiimikada Ruifu waa soo saaraha ugu horreeya ee 3-Nitrophthalic Anhydride (CAS: 641-70-3) oo leh tayo sare, dhexdhexaad ah Pomalidomide (CAS: 19171-19-8).Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso 3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | 3-Nitrophthalic anhydride |
| La mid ah | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dion;4-Nitroisobenzofuran-1,3-Dion;4-Nitro-1,3-isobenzofurandione;Pomalidomide wasakh A |
| Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
| Lambarka CAS | 641-70-3 |
| Qaanuunka molecular | C8H3NO5 |
| Miisaanka Molecular | 193.11 g/mol |
| Meesha dhalaalaysa | 161.0 ilaa 165.0 ℃ |
| Xasaasi ah | Qoyaanka xasaasiga ah |
| Biyuhu milmayn | Waxaa laga yaabaa inay ku qudhunto biyaha |
| COA & MSDS | La heli karo |
| Asal ahaan | Shanghai, Shiinaha |
| Summada | Kiimikada Ruifu |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Jaal fudud ilaa Irbad Jaalle Crystal ama budada Crystalline | U hogaansama |
| Meesha dhalaalaysa | 161.0 ~ 165.0 ℃ | 163.0 ~ 165.0 ℃ |
| Khasaare xagga qalajinta | <0.50% | 0.10% |
| Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) | 98.85% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| 1H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
| Codsiga | Dhexdhexaadiyaha Pomalidomide (CAS: 19171-19-8) | |
Xidhmada:Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
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Xeerarka Khatarta
36/37/38 - Cuncun xagga indhaha, habka neefsashada iyo maqaarka.
Sharaxaada Badbaadada
S26 - Haddii ay dhacdo in indhaha la taabto, isla markiiba ku raaci biyo badan oo raadso talo caafimaad.
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3-Nitrophthalic Anhydride (CAS: 641-70-3) waxaa loo isticmaalaa dhexdhexaadinta Pomalidomide (CAS: 19171-19-8).Bishii Febraayo 2013, US FDA waxay ansixisay Pomalidomide daawaynta Multiple myeloma (MM) ee bukaanada qaba horumarka cudurka ka dib markii la helo daaweynta kale ee kansarka.Pomalidomide waa 4-amino analoog ee thalidomide oo leh awood la xoojiyey iyo astaanta sunta oo la roonaaday.Pomalidomide iyo thalidomide waxay sameeyaan saameyntooda iyagoo wax ka beddelaya difaaca, ka hortagga angiogenesis, faragelinta lafaha / buro microenvironment, iyo xakameynta borotiinka cereblon.Pomalidomide ayaa si xoog leh u joojisay faafitaanka vitro ee noocyada kala duwan ee xadadka unugyada MM ee bini'aadamka, IC50 ~ 10 nM, halka thalidomide ay muujisay ku dhawaad wax xannibaad ah ilaa 100 μM.Noocyada burooyinka MM ee jiirka, 50 mg / kg qiyaasta maalinlaha ah ee pomalidomide waxay keentay xannibaad muuqda oo koritaanka burada ka dib 15 maalmood oo daaweyn ah iyo dib-u-celin dhammaystiran gudaha 3-6 toddobaad oo ka soo horjeeda kontaroolada thalidomide-la daweeyay isla qiyaas isku mid ah.Pomalidomide waxaa lagu diyaariyaa uumi 3-Nitrophthalic Anhydride oo leh 3-Aminopperidine-2,6-Dion oo ay ku xigto hydrogenation catalytic ee kooxda nitro.
