3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9 Olaparib Warshada Dhexe
Nadiif Sarreysa, Wax Soo Saarka Ganacsiga
Olaparib iyo Dhexdhexaadiyeyaasha la xidhiidha:
Olaparib CAS 763113-22-0
2-Fluoro-5-Formylbenzonitrile CAS 218301-22-5
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl) benzoic acid CAS 763114-26-7
1-(Cyclopropylcarbonyl) Piperazine Hydrochloride CAS 1021298-67-8
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid CAS 61260-15-9
| Magaca Kiimikada | 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid |
| La mid ah | Dimethyl 3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonate |
| Lambarka CAS | 61260-15-9 |
| Lambarka CAT | RF-PI453 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C10H11O5P |
| Miisaanka Molecular | 242.17 |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada cad ama ku dhawaad cad |
| daahirnimo | ≥98.0% |
| Qoyaanka (KF) | ≤0.50% |
| Wadarta wasakhda | ≤2.0% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Olaparib (CAS: 763113-22-0) PARP-Inhibitor |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
3-Oxo-1,3-Dihydroisobenzofuran-1-Ylphosphonic Acid (CAS: 61260-15-9), dhexe ee Olaparib (CAS: 763113-22-0).Olaparib waa nooc ka mid ah horjoogayaasha poly ADP-ribose polymerase (PARP), oo ay ku jiraan PARP1, PARP2, iyo PARP3.PARP waxay dhexdhexaadisaa habka DNA-dayactirka kaas oo door muhiim ah ka ciyaara hagaajinta dhaawaca DNA iyo apoptosis, sidaas darteed olaparib wuxuu si gaar ah u bartilmaameedsadaa habka dayactirka DNA ee hagaajinta unugyada DNA-da oo uu saameyn ku yeesho isagoo weeraraya nuglaanta muhiimka ah ee unugyada kansarka ee sida isbeddelka BRCA1 iyo BRCA2.Farsamadan awgeed, waxaa loo isticmaali karaa daawaynta dayactirka bukaanada qaba kansarka ugxansidaha soo noqnoqda ee soo noqnoqda kaas oo leh isbeddellada u nuglaanta kansarka naasaha (BRCA) iyo sidoo kale u nugul daroogada platinum.
