4-Benzyl-2-Hydroxymorpholin-3-hal CAS 287930-73-8 daahirnimo>99.0% (HPLC) Warshad Dhexdhexaad ah
Soo saaraha iyo alaab-qeybiyaha hormuudka ka ah
Dhexdhexaadiyaha Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-hal CAS 287930-73-8
(R) -1-[3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2
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| Magaca Kiimikada | 4-Benzyl-2-Hydroxymorpholin-3-kow |
| La mid ah | 4-Benzyl-2-Hydroxy-Morpholin-3-hal;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Xumaan-xumada Aprepitant 48;Fosaprepitant wasakh 23;Dhexdhexaadiyaha dhexdhexaadka ah Ⅱ |
| Lambarka CAS | 287930-73-8 |
| Lambarka CAT | RF2660 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C11H13NO3 |
| Miisaanka Molecular | 207.23 |
| Meesha dhalaalaysa | 134.0 ilaa 138.0 ℃ |
| Barta Karsan | 441.7± 45.0 ℃ |
| Cufnaanta | 1.292± 0.06 g/cm3 |
| Ku milmay biyaha | DMSO (wax yar), Methanol (wax yar, kuleyl) |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystal White ilaa Cadaan |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
| Meesha dhalaalaysa | 134.0 ilaa 138.0 ℃ |
| Biyaha (waxaa qoray Karl Fischer) | <0.50% |
| Hadhaaga dabka | <0.20% |
| Wadarta wasakhda | <1.00% |
| Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Aprepitant (CAS: 170729-80-3) Daawooyinka Antiemetic |
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Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
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4-Benzyl-2-Hydroxymorpholin-3-one (CAS: 287930-73-8), waa dhexdhexaad ah Aprepitant (CAS: 170729-80-3), loo isticmaalo sida daawooyinka antiemetic.Aprepitant waa neurokinin-1 (NK-1) antagonist soo dhaweeye waxaana iska leh wakiilada daweynta matagga inta lagu jiro kiimoterabiga kansarka.Waxaa markii ugu horreysay si guul leh u soo saartay Shirkadda Merck (Jarmalka).Bishii Maarso 2003, Maamulka Cuntada iyo Dawooyinka ee Mareykanka ayaa oggolaaday in loo isticmaalo daawaynta matagga kemotherabi.Alaabtani waxa ay leedahay xulafo aad u saraysa oo ay la leedahay bini'aadamka halka ay hoosayso xidhiidhka serotonin, dopamine iyo glucocorticoid receptor affinity.Aprepitant, marka lagu daro 5-HT3 reseptor inhibitors (sida ondansetron hydrochloride) iyo corticosteroid dexamethasone, waxay sii yareyn kartaa cisplatin-ku-soo-baxa ba'an iyo (ama) dib-u-dhac ku yimaada.Codsashada daawadan oo keliya waxay yeelan kartaa xoogaa ka hortag ah.
![(R) -1- [3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2 daahirnimo> 99.0% (GC) Dhexdhexaadiyaha](https://www.ruifuchemical.com/uploads/R-1-35-Bistrifluoromethylphenylethanol-CAS-127852-28-2-300x300.jpg)