4′-(Methylsulfonyl) acetophenone CAS 10297-73-1 daahirnimo>99.0% (HPLC)
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Magaca Kiimikada | 4'-(Methylsulfonyl) acetofenone |
La mid ah | 4- (Methylsulfonyl) acetofenone;4-Methylsulphonylacetophenone;4-Methyi Sulfonyl Acetofenone;4-(Methyl Sulfonyl) Acetophenone;1- (4- (Methylsufonyl) phenyl) ethanone;1-[4- (Methylsulfonyl) phenyl] ethan-1-hal;p-Acetylfenyl Methyl Sulfone;p-Methylsulfonylacetofenone;Etoricoxib Impurity A (USP Compound A) |
Lambarka CAS | 10297-73-1 |
Lambarka CAT | RF2932 |
Heerka Saamiyada | Kaydka dhexdiisa, Awood Wax-soo-saar 20 Tan bishii |
Qaanuunka molecular | C9H10O3S |
Miisaanka Molecular | 198.24 |
Meesha dhalaalaysa | 126.0 ~ 129.0 ℃ (lit.) |
Heerka khatarta | Xanaaqsan |
Koodhka HS | 29144000 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Crystal huruud ah oo caddaan ah |
Daahirnimada / Habka Falanqaynta | >99.0% (GC) |
Meesha dhalaalaysa | 126.0 ~ 129.0 ℃ |
Biyaha (waxaa qoray Karl Fischer) | <0.50% |
Wadarta wasakhda | <1.00% |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyeyaasha Daawooyinka |
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4'-(Methylsulfonyl) acetophenone (CAS: 10297-73-1) waa walxo ceeriin ah oo muhiim ah iyo dhexdhexaad ah oo loo isticmaalo isku-dhafka dabiiciga ah, daawooyinka.4'-(Methylsulfonyl) acetofenone waa wasakhda Etoricoxib (CAS: 202409-33-4), kaas oo ah xakameyn gaar ah oo COX-2 ah.Etoricoxib waa nooc ka mid ah cyclooxygenase-2 (COX-2) horjoogayaasha aadka loo xushay ee ay samaysay shirkadda Merck.Etoricoxib waxaa markii ugu horreysay loo oggolaaday inuu soo galo suuqa 2002 gudaha Boqortooyada Midowday, waxaana ku xigay waddamada suuq geynta iyo gobollada ay ku jiraan Midowga Yurub, Aasiya, Australia iyo Laatiin Ameerika.Ilaa dhammaadka 2013, waxaa loo oggolaaday suuq-geynta 97 waddan si loogu isticmaalo daaweynta osteoarthritis (OA), rheumatoid arthritis-ka, ankylosing spondylitis, xanuunka dhabarka hoose ee joogtada ah, gouty arthritis-ka, dysmenorrhea aasaasiga ah iyo xanuunka ka dib, iyo kuwa kale. cudurada.Etoricoxib waxa kale oo uu suuqa ka galay Taiwan iyo Hong Kong ee Shiinaha.Waxay suuqa ka soo gashay dhul weynaha Shiinaha 2008dii iyada oo calaamadaha la ansixiyay ay yihiin gouty arthritis-ka ba'an iyo OA iyo calaamad kale oo ah dysmenorrhea aasaasiga ah qeybtii labaad ee 2014.