4-(Methylsulfonyl) phenylacetic Acid CAS 90536-66-6 daahirnimo>99.5% (HPLC) Warshada Dhexe ee Etoricoxib
Soo saaraha iyo alaab-qeybiyaha ugu horreeya, Dhexdhexaadiyeyaasha Etoricoxib
Etoricoxib API CAS 202409-33-4
4-(Methylthio) Phenylacetic Acid CAS 16188-55-9
4-(Methylsulfonyl) Phenylacetic Acid CAS 90536-66-6
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Magaca Kiimikada | 4-(Methylsulfonyl) phenylacetic acid |
La mid ah | 4-Methylsulphonylphenylacetic acid;4-(Methanesulfonyl) Acid phenylacetic;(4-Methanesulfonylphenyl) acetic acid;4-Methylsulfonyl Phenyl Acetic Acid;2- (4- (Methylsulfonyl) phenyl) acetic acid;[p-(Methylsulfonyl) phenyl]-Acetic Acid;4-Mesylphenylacetic acid |
Lambarka CAS | 90536-66-6 |
Lambarka CAT | RF-PI1182 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C9H10O4S |
Miisaanka Molecular | 214.24 |
Meesha dhalaalaysa | 136.0 ilaa 140.0 ℃ |
Cufnaanta | 1.35 |
Solubility | Ku milma Methanol |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Adag ee Cadaan iyo Off-cad |
Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) |
Meesha dhalaalaysa | 136.0 ilaa 140.0 ℃ |
Qoyaanka (KF) | <0.50% |
Xumaanta Ugu Weyn Keliya | <0.30% |
Wadarta wasakhda | <0.50% |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadka Etoricoxib (CAS: 202409-33-4) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
4-(Methylsulfonyl) phenylacetic Acid (CAS: 90536-66-6) waa dhexdhexaadiye Etoricoxib (CAS: 202409-33-4).Etoricoxib waa nooc ka mid ah cyclooxygenase-2 (COX-2) horjoogayaasha aadka loo xushay ee ay samaysay shirkadda Merck.Etoricoxib waxaa si weyn loogu isticmaalaa daawaynta osteoarthritis (OA), rheumatoid arthritis-ka, ankylosing spondylitis, xanuunka dhabarka hoose ee joogtada ah, gouty arthritis-ka, dysmenorrhea aasaasiga ah iyo xanuunka qalliinka kadib, iyo cuduro kale.Etoricoxib, oo ah COX-2 inhibitor oo la xushay, ayaa leh anti-bararka, xanuunka xanuunka iyo saamaynta antipyretic, oo ku habboon daaweynta calaamadaha iyo calaamadaha osteoarthritis ba'an iyo daba-dheer, iyo sidoo kale gouty arthritis-ka ba'an.Etoricoxib si degdeg ah ayaa loo nuugo, oo leh bioavailability afka ah oo ah 80 ilaa 100%, oo wuxuu gaaraa uruurinta balaasmaha ugu badnaan 1 ilaa 2 saacadood ka dib qiyaasta.Cuntadu waxay hoos u dhigtaa heerka nuugista laakiin wax saamayn ah kuma laha heerka nuugista.Waxay muujinaysaa ciribtirka dheer ee nolosha nuska ah ee ku dhawaad 22 saacadood, taasoo muujinaysa farmashiyaha plasma linear oo aan lahayn wax ururin inta lagu jiro qiyaaso badan.