5- (2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Nadiifinta Dhexdhexaadka ah ≥99.0%
Supply Vonoprazan Fumarate iyo Dhexdhexaadiyaha La Xiriira
5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Magaca Kiimikada | 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde |
| La mid ah | Vonoprazan Fumarate (TAK-438) Dhexdhexaad 3 |
| Lambarka CAS | 881674-56-2 |
| Lambarka CAT | RF-PI330 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C11H8FNO |
| Miisaanka Molecular | 189.19 |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Jaalle ilaa Bunni budada |
| Meesha dhalaalaysa | 122.0 ~ 131.0 ℃ |
| Aqoonsiga: RT(HPLC) | Waafaqsan Heerka Tixraaca |
| Khasaaraha Qalajinta | ≤0.50% |
| Hadhaaga Dabka | ≤0.50% |
| Walxaha laxidhiidha | |
| daahirnimo | ≥99.0% |
| Xumaan Keli ah | ≤0.50% |
| Wadarta wasakhda | ≤1.0% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Vonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
Xidhmada: Dhalo, boorsada bireed aluminium, durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
5- (2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) waxay u shaqeysaa sidii reagent ee diyaarinta synthetic ee derivatives pyrrole novel sida xannibaadaha acid-potassium-tartanka leh (P-CAB).5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde waa dhexdhexaadiyaha Vonoprazan Fumarate (CAS 1260141-27-2).Vonoprazan fumarate (Takecab®), oo ay heleen oo ay horumariyeen Takeda iyo Otsuka, waxaa ansixiyay PMDA ee Japan Diseembar 2014, waxaana loo tilmaamay daaweynta boogaha gastric, boogaha duodenal iyo reflux esophagitis.Vonoprazan fumarate wuxuu leeyahay hab cusub oo ficil ah oo loo yaqaan 'potassium-competitive acid blockers', kaas oo si tartan ah u xakameynaya xiritaanka ions potassium si H +, K+-ATPase (oo sidoo kale loo yaqaan bamka proton) ee tallaabada ugu dambeysa ee dheecaanka acid gastric ee unugyada parietal gastric.Vonoprazan ma joojiso dhaqdhaqaaqa Na+, K+-ATPase xitaa 500 jeer ka sarreeya qiimaha IC50 ee ka soo horjeeda dhaqdhaqaaqa H+, K+-ATPase.Intaa waxaa dheer, daroogada ma saameynayso gobolka sirta ah ee caloosha, si ka duwan PPIs.
