5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Warshada Dhexe
Soo-saarka wax-soo-saarka, Nadiifinta Sare, Wax-soo-saarka Ganacsiga
Dapagliflozin (CAS: 461432-26-8) Dhexdhexaadiyeyaasha la xidhiidha:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Magaca Kiimikada | 5-Bromo-2-Chlorobenzoic Acid |
| La mid ah | 2-Chloro-5-Bromobenzoic Acid |
| Lambarka CAS | 21739-92-4 |
| Lambarka CAT | RF-PI439 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C7H4BrClO2 |
| Miisaanka Molecular | 235.46 |
| Meesha dhalaalaysa | 154.0 ilaa 156.0 ℃ ( shid) |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Ka-bax-caddan ilaa budada jaalaha ah ee khafiifka ah |
| Qiimayn | ≥99.0% |
| Biyaha (KF) | ≤0.50% |
| Hadhaaga dabka | ≤0.30% |
| 2-Chlorobenzoic Acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Wadarta wasakhda | ≤1.0% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadka Dapagliflozin (CAS: 461432-26-8), nooca II ee sonkorowga |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) waxaa loo isticmaalaa sidii walxo bilow ah ee isku dhafka Dapagliflozin (CAS: 461432-26-8), soodhiyam-glucose cotransporter-2 inhibitor ah oo la xushay oo yareeya kelyaha dib u nuugista gulukooska waxaana loo isticmaalaa in lagu daweeyo bukaanada qaba nooca II ee sonkorowga.Dapagliflozin waa SGLT-2 (SLC5A2) horjooge awood leh oo door ah oo leh EC50 ee 1.1 nM.Waxay leedahay daalacnaan wanaagsan oo dhan xuubabka unugyada Caco-2 waxayna u tahay substrate P-glycoprotein (P-gp).Dapagliflozin waxaa ansixiyay FDA 2012.
