6-Nitroindazole CAS 7597-18-4 daahirnimo>98.0% (GC) Warshada
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Magaca Kiimikada | 6-Nitroindazole |
La mid ah | 6-Nitro-1H-Indazole;6-Nitro-1 (2) H-Indazole;6-Nitro-Indazole |
Lambarka CAS | 7597-18-4 |
Lambarka CAT | RF2675 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C7H5N3O2 |
Miisaanka Molecular | 180.0 ilaa 184.0163.14 |
Cufnaanta | 1.525 |
Solubility in methanol kulul | Turbidity Aad u Daciif ah |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Jaalle fudud ilaa budo bunni ah |
Daahirnimada / Habka Falanqaynta | >98.0% (GC) |
Meesha dhalaalaysa | 180.0 ilaa 184.0 ℃ |
Khasaare xagga qalajinta | <1.00% |
Wadarta wasakhda | <2.00% |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyeyaasha Daawooyinka |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
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Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
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6-Nitroindazole (CAS: 7597-18-4) waxaa loo istcimaalaa dhexdhexaadka dawooyinka, Axitinib/AG013736 Dhexdhexaadiye.Axitinib (AG-013736) waa horjooge badan oo bartilmaameed u ah VEGFR1, VEGFR2, VEGFR3, PDGFRβ iyo c-Kit oo leh IC50 ee 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM iyo 1.7 nM, siday u kala horreeyaan.Axitinib waa tyrosine kinase inhibitor ah.Axitinib waxaa loo isticmaalaa daaweynta kansarka.Bishii Janaayo 2012, US FDA waxay ansixisay axitinib (sidoo kale loo yaqaan AG-013736) daaweynta kansarka unugyada sare ee kelyaha (RCC) ee bukaanada aan ka jawaabin daawaynta hore.Axitinib waa digsiga VEGF inhibitor wuxuuna u shaqeeyaa isagoo ku xiraya intracellular tyrosine kinase catalytic domain ee VEGF taasoo horseedaysa xannibaadda calaamadaynta iyada oo loo marayo dariiqan angiogenic.