6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9 PF-07321332 Boceprevir Sawirka Dhexdhexaadka ah

6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9 PF-07321332 Boceprevir Intermediate

Sharaxaad Gaaban:

Magaca Kiimikada: 6,6-Dimethyl-3-azabicyclo[3.1.0] hexane

CAS: 943516-54-9

Muuqashada: Dareere hufan oo aan Midab lahayn

Daahirsanaanta: ≥98.0%

Dhexdhexaadiyaha PF-07321332 Paxlovid (CAS 2628280-40-8) iyo Boceprevir (CAS 394730-60-0)

Tayada Sare, Wax Soo Saarka Ganacsiga

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Sharaxaad:

Iibka Ganacsiga PF-07321332 Dhexdhexaadiyeyaasha la xidhiidha Paxlovid oo leh tayo Sare
L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl] propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0] hexane CAS 943516-54-9

Guryaha Kiimikada:

Magaca Kiimikada	6,6-Dimethyl-3-azabicyclo[3.1.0] hexane
Lambarka CAS	943516-54-9
Lambarka CAT	RF-PI316
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C7H13N
Miisaanka Molecular	111.18
Barta Karsan	135 ℃
Cufnaanta	0.911
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Dareere Daahsoon oo aan Midab lahayn
daahirnimo	≥98.0%
Xumaanta Keliya	≤0.50%
Wadarta wasakhda	≤2.0%
Biraha culus	≤20pm
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadiyaha PF-07321332 Paxlovid (CAS 2628280-40-8) iyo Boceprevir (CAS 394730-60-0)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

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FAQ:

Codsiga:

6,6-Dimethyl-3-azabicyclo[3.1.0] hexane (CAS 943516-54-9) waa dhexe ee PF-07321332 Paxlovid (CAS 2628280-40-8) iyo Boceprevir (CAS 394730-60-0).Pfizer's Paxlovid PF-07321332 waa daawaynta afka laga qaato ee ka hortagga fayraska ee lagu beegsanayo SARS-CoV-2 betacoronavirus si looga hortago COVID-19.Paxlovid waa protease ka hortag ah oo muujiyay firfircoonida fayraska fayraska ee ka soo horjeeda SARS-CoV-2 iyo coronaviruses kale, taasoo soo jeedinaysa suurtagalnimada in loo isticmaalo daawaynta COVID-19, iyo sidoo kale isticmaalka suurtagalka ah ee ka hortagga khataraha fayraska mustaqbalka, ayuu yidhi Pfizer.Boceprevir (EBP 520) waa mid awood leh, aad u xushay, afka laga heli karo HCV NS3 protease inhibitor oo leh Ki of 14 nM labadaba enzyme assay iyo EC90 ee 350 nM ee baaritaanka unugyada ku salaysan.Boceprevir waxay joojisaa dhaqdhaqaaqa SARS-CoV-2 3CLpro.