![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3 Tolvaptan Dhexdhexaad Sawirka](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3.jpg)
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3 Tolvaptan Intermediate
Soo-saarka wax-soo-saarka, Tayada Sare, Wax-soo-saarka Ganacsiga
Tolvaptan iyo Dhexdhexaadiyayaasha la xidhiidha:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Magaca Kiimikada | 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal |
| La mid ah | 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-hal;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H) -hal |
| Lambarka CAS | 160129-45-3 |
| Lambarka CAT | RF-PI395 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C10H10ClNO |
| Miisaanka Molecular | 195.65 |
| Meesha dhalaalaysa | 103.0 ilaa 107.0 ℃ |
| Solubility | Ku milma Methanol |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Cagaar khafiifa ilaa budada jaalaha ah ee fudud |
| Hababka Aqoonsiga | NMR, HPLC |
| Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
| Khasaare xagga qalajinta | ≤1.0% |
| Hadhaaga dabka | ≤0.50% |
| Xumaan Keli ah | ≤0.50% |
| Wadarta wasakhda | ≤1.0% |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Tolvaptan (CAS 150683-30-0), daaweynta Hyponatremia |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one (CAS 160129-45-3) waa dhex dhexaad u ah isku dhafka Tolvaptan (CAS 150683-30-0).Tolvaptan waa doorasho, tartan afka ah oo firfircoon oo aan peptide ahayn arginine vasopressin V2 antagonist leh IC50 ee 1.28µM ee ka hortagga isu-ururinta platelet-ka ee AVP.Tolvaptan waxaa loo isticmaalaa in lagu daweeyo hyponatremia ee la xiriirta wadne-gabka wadnaha, cirrhosis, iyo cilladda hormoonka antidiuretic ee aan habboonayn.Tolvaptan sidoo kale wuxuu ku jiraa tijaabooyin caafimaad oo degdeg ah oo loogu talagalay cudurka kelyaha ee polycystic.Daawaynta Tolvaptan waxay sababtaa dhimista miisaanka jidhka oo degdeg ah oo joogto ah iyadoo la raacayo korodhka wax soo saarka kaadida, wanaajisa iyo/ama caadi ka dhigta serum sodium ee bukaanka hyponatremic, waxay yaraynaysaa calaamadaha iyo calaamadaha ciriiriga waxayna kordhisaa haraadka.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
