7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 daahirnimo>99.0% (HPLC) Afatinib Dimaleate Warshada Dhexdhexaadka ah Sawirka

7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 daahirnimo>99.0% (HPLC) Afatinib Dimaleate Warshada Dhexe

Sharaxaad Gaaban:

Magaca: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Daahirsanaanta:>99.0% (HPLC)

Muuqashada: Jaalle fudud ilaa budada bunni fudud

Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

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Sharaxaad:

Dhexdhexaadiyaha Keenida Kiimikada Ruifu ee Afatinib
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Afatiib Dimaleate CAS 850140-73-7
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Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-hal CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
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Guryaha Kiimikada:

Magaca Kiimikada	7-Chloro-6-Nitro-4-Hydroxyquinazoline
La mid ah	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-hal;7-Chloro-6-Nitroquinazolin-4(3H) -hal
Lambarka CAS	53449-14-2
Lambarka CAT	RF-PI2030
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C8H4ClN3O3
Miisaanka Molecular	225.59
Dareenka	Xasaasida kulaylka
Solubility	Waxoogaa Ku Soluble Dimethylformamide
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Jaalle fudud ilaa budo bunni ah
Aqoonsiga (HPLC)	Wakhtiga haynta ee muunadu waa inay la mid tahay heerka
Daahirnimada / Habka Falanqaynta	>99.0% (HPLC)
Meesha dhalaalaysa	300.0 ~ 303.0 ℃
Waxyaabaha Biyaha (KF)	<0.50%
Hadhaaga dabka	<0.30%
Xumaanta 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Xumaanta 2	<0.50% (5,7-Dichloro-4[1H] quinazolinone)
Xumaanta 3	<1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
Xumaanta Keliga ah ee Kale	<0.20%
Wadarta wasakhda	<1.00%
Biraha culus (sida Pb)	<20ppm
Infrared Spectrum	Waafaqsan Qaab-dhismeedka
Proton NMR Spectrum	Proton NMR Spectrum
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadka Afatiib, Afatiib Dimaleate

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

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FAQ:

Codsiga:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) waa dhexe ee Afatinib Dimaleate (CAS: 850140-73-7).Afatinib waa qooyska ErbB ee xannibayayaal ah oo aan la beddeli karin kuwaas oo xakameynaya gudbinta macluumaadka oo xannibaya waddooyinka waaweyn ee ku lug leh koritaanka unugyada kansarka iyo kala qaybinta.Sababtoo ah habka gudbinta macluumaadka qoyska ErbB waxaa kicin kara homodimers badan iyo heterodimers, xannibaad isku mar ah xubno badan oo qoyska ErbB ah (sida EGFR, HER2, ErbB3 iyo ErbB4) waxay si wax ku ool ah u joojin kartaa gudbinta macluumaadka hoose.Aftiinib waxa loo isticmaalaa in lagu daweeyo nooc gaar ah oo kansarka sanbabada ah (kansar sambabada unugyada aan yarayn) kaas oo ku faafay qaybaha kale ee jidhka.Waxay ka tirsan tahay fasalka dawooyinka loo yaqaan kinase inhibitors.Waxay u shaqeysaa iyadoo hoos u dhigaysa ama joojinaysa koritaanka unugyada kansarka.Waxay ku xidhaa borotiin gaar ah (epidermal receptor-EGFR) ee burooyinka qaarkood.