7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Dhexdhexaad Nadiif Sare
Soo saaraha soo saaraha Irinotecan iyo Dhexdhexaadiyayaasha la xidhiidha:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Saldhigga Bilaashka ah CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Magaca Kiimikada | 7-Ethyl-10-Hydroxycamptothecin |
La mid ah | SN-38 |
Lambarka CAS | 86639-52-3 |
Lambarka CAT | RF-PI242 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C22H20N2O5 |
Miisaanka Molecular | 392.41 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada kiristaalo ee Jaallaha fudud |
Aqoonsiga (IR, UV) | (1) Ultraviolet nuugista spectrum spectrum waa waafaqsan baahida (2) Xidhiidhka nuugista shucaaca infrared-ka leh spectrum heerka tixraaca waa inuu u hoggaansamaa imtixaanada la ansixiyay. |
Meesha dhalaalaysa | 228.0 ~ 235.0 ℃ |
Walxaha laxidhiidha | ≤1.5% |
10-Hydroxycamptothecin | ≤0.30% |
7-Cthylcamptothecin | ≤0.70% |
Xumaanta ugu badan ee aan la garanayn | ≤0.50% |
Khasaare xagga qalajinta | ≤1.0% |
Biraha culus | ≤10pm |
Hadhaaga dabka | ≤0.10% |
Cadaynta Xalka | Cad |
Qiimayn | ≥98.0% (HPLC) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Dawada ee Irinotecan |
Xidhmada: Dhalo, boorsada bireed aluminium, durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
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Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) oo leh tayo sare leh.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) waa metabolite firfircoon ee Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) waxay joojisaa DNA-ga iyo isku-dhafka RNA ee IC50s ee 0.077 iyo 1.3 μM, siday u kala horreeyaan.7-Ethyl-10-Hydroxycamptothecin (SN-38), waa metabolite firfircoon ee Irinotecan, derivative semisynthetic of camptothecin, alkaloid quinoline ku salaysan oo laga helay jilif geed Chinese camptotheca iyo geed nothapodytes Asian.In kasta oo 7-Ethyl-10-Hydroxycamptothecin ay 1,000 jeer ka awood badan tahay Irinotecan, looma beddelin musharrax daroogo macquul ah sababtoo ah waa mid aan la milmi karin.Hadda waxa la mariyaa tijaabooyin caafimaad oo ay weheliso unugyo kale kuwaas oo ugu dambeyntii u oggolaan kara inay noqoto mid waxtar u leh daawada antineoplastic.