7-Fluoro-6-Nitroquinazolin-4(1H)-hal CAS 162012-69-3 daahirnimo>99.0% (HPLC) Afatinib Dimaleate Warshada Dhexdhexaadinta Sawirka

7-Fluoro-6-Nitroquinazolin-4(1H)-hal CAS 162012-69-3 daahirnimo>99.0% (HPLC) Afatiib Dimaleate Warshada Dhexe

Sharaxaad Gaaban:

Magaca Kiimikada: 7-Fluoro-6-Nitroquinazolin-4(1H) -hal

CAS: 162012-69-3

Daahirsanaanta:>99.0% (HPLC)

Jaalle ilaa casaan huruud ah ama budo

Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

Tayada Sare, Wax Soo Saarka Ganacsiga

E-Mail: alvin@ruifuchem.com

Email noogu soo dir

Faahfaahinta Alaabta

Alaabooyinka La Xiriira

Tags Product

Sharaxaad:

Dhexdhexaadiyaha Keenida Kiimikada Ruifu ee Afatinib
Afatirib CAS 439081-18-2
Afatiib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-hal CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Guryaha Kiimikada:

Magaca Kiimikada	7-Fluoro-6-Nitroquinazolin-4(1H) -hal
La mid ah	7-Fluoro-6-Nitroquinazolin-4(3H) -hal;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-hal
Lambarka CAS	162012-69-3
Lambarka CAT	RF-PI2025
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C8H4FN3O3
Miisaanka Molecular	209.13
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Jaalle ilaa casaan huruud ah ama budo
1 H NMR Spectrum	Waafaqsan Qaab-dhismeedka
Daahirnimada / Habka Falanqaynta	>99.0% (HPLC)
Khasaare xagga qalajinta	<0.50%
Wadarta wasakhda	<1.00%
Proton NMR Spectrum	Waafaqsan Qaab-dhismeedka
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadiyaha Afatiib Dimaleate (CAS: 850140-73-7)

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka

FAQ:

Codsiga:

7-Fluoro-6-Nitroquinazolin-4(1H) -hal (CAS: 162012-69-3) waa dhex dhexaad ka ah Afatinib Dimaleate (CAS: 850140-73-7).Afatinib waa qooyska ErbB ee xannibayayaal ah oo aan la beddeli karin kuwaas oo xakameynaya gudbinta macluumaadka oo xannibaya waddooyinka waaweyn ee ku lug leh koritaanka unugyada kansarka iyo kala qaybinta.Sababtoo ah habka gudbinta macluumaadka qoyska ErbB waxaa kicin kara homodimers badan iyo heterodimers, xannibaad isku mar ah xubno badan oo qoyska ErbB ah (sida EGFR, HER2, ErbB3 iyo ErbB4) waxay si wax ku ool ah u joojin kartaa gudbinta macluumaadka hoose.Afatinib waa daawo loo oggolaaday daawaynta kansarka sanbabada unugyada aan-yaraha ahayn (NSCLC), oo uu sameeyay Boehringer Ingelheim.Waxay u shaqeysaa sidii xakameynta angiokinase.Sida lapatinib iyo neratinib, afatinib waa tyrosine kinase inhibitor (TKI) kaas oo sidoo kale si aan kala go 'lahayn u joojinaya fayraska koritaanka epidermal ee bini'aadamka 2 (Her2) iyo soo-dhoweeyaha koritaanka epidermal (EGFR) kinases.Afatinib kaliya kama soo horjeedo isbeddellada EGFR ee ay bartilmaameedsanayaan jiilka kowaad TKIs likeerlotinib ama gefitinib, laakiin sidoo kale ka soo horjeeda kuwa aan xasaasi u ahayn daawaynta caadiga ah.Sababtoo ah waxqabadkeeda dheeraadka ah ee ka dhanka ah Her2, waxaa laga baarayaa kansarka naasaha iyo sidoo kale EGFR iyo kansarrada kale ee Her2.