7-Methoxy-1-Tetralone CAS 6836-19-7 daahirnimo>99.0% (GC) Warshada Dhexdhexaadka ah ee Aomelatine
Soo saaraha hormuudka ah iyo iibiyaha Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
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| Magaca Kiimikada | 7-Methoxy-1-Tetralone |
| La mid ah | 3,4-Dihydro-7-Methoxy-1 (2H) -Naphthalenone;7-Methoxy-3,4-Dihydro-2H-Naphthalen-1-hal;7-Methoxy-1-oxo-Tetralin;7-Methoxy-1,2,3,4-Tetrahydronaphthalene-1-hal;7-Methoxy-1-Oxotetraline;7-Methoxy-1-Tetralinone;7-Methoxytetralin-1-hal;Dhexdhexaadiyaha Agomelatine B |
| Lambarka CAS | 6836-19-7 |
| Lambarka CAT | RF2689 |
| Heerka Saamiyada | Kaydka dhexdiisa, Awood Wax-soo-saar 30 Tan bishii |
| Qaanuunka molecular | C11H12O2 |
| Miisaanka Molecular | 176.22 |
| Meesha dhalaalaysa | 60.0 ilaa 64.0 ℃ |
| Cufnaanta | 1.124±0.06 g/cm3 |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Cadaan ilaa Bunni ah Crystals ama budada |
| Daahirnimada / Habka Falanqaynta | >99.0% (GC) |
| Meesha dhalaalaysa | 60.0 ilaa 64.0 ℃ |
| Biyaha (waxaa qoray Karl Fischer) | <0.50% |
| Hadhaaga dabka | <0.10% |
| Xumaanta Keliya | <0.50% |
| Wadarta wasakhda | <1.00% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
| Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Dawada;Agomelatine (CAS 138112-76-2) Dhexdhexaad |
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7-Methoxy-1-Tetralone (CAS: 6836-19-7) waa dhexdhexaad Aomelatine (CAS: 138112-76-2).Agomelatine waa daawada niyad-jabka melatonergic ee ay soo saartay shirkadda dawooyinka ee Servier.Waxaa loo suuq geeyaa daaweynta xanuunka weyn ee niyad-jabka waxaana lagu soo warramey inaysan soo saarin xanuunka joojinta oo aysan lahayn wax saameyn ah oo galmo ah marka loo eego SSRIs, SNRIs iyo antidepressants tricyclic ka weyn.Agomelatine waxa kale oo laga yaabaa inay saameyn togan ku yeelato hurdada.1. Farmashiye ahaan, Agomelatine waxaa loo isticmaalaa daawaynta xanuunka weyn ee niyad-jabka, xanuunka shucuureed.2. Agomelatine waxaa loo isticmaalaa daawaynta xanuunka weyn ee niyad-jabka, xanuunka shucuureed.Walaxda dawada ee habdhiska neerfaha.Daawooyinka niyad-jabka, anxiolytic, hagaajinta laxanka hurdada iyo habaynta saacada noolaha.3. Agomelatine waa agonist melatoninergic iyo antagonist xulashada 5-ht2c reseptors.4. Agomelatine waa daawada niyad-jabka.Waxaa loo kala saaraa sida norepinephrine-dopamine disinhibitor (NDDI) sababtoo ah ka soo horjeeda soo-dhoweeyaha 5-HT2C.5. Agomelatine sidoo kale waa agonist awood leh oo ka shaqeeya melatonin reseptors taas oo ka dhigaysa daawada niyad-jabka ee melatonergic ee ugu horreysa.
