8-Hydroxy-5-Nitroquinoline CAS 4008-48-4 daahirnimo>97.0% (HPLC)
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Magaca Kiimikada | 8-Hydroxy-5-Nitroquinoline |
La mid ah | 5-Nitro-8-Quinolinol;Nitroxoline;8-Nitroquinolin-5-ol;5-Nitroquinolin-8-ol;5-Nitro-8-Hydroxyquinoline |
Lambarka CAS | 4008-48-4 |
Lambarka CAT | RF2381 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C9H6N2O3 |
Miisaanka Molecular | 190.16 |
Cufnaanta | 1.496 |
Xasaasi ah | Xasaasi Fudud, Dareen Hawada |
Solubility | Aan lagu milmi karin EtOH;Aan lagu milmin H2O;≥118.4 mg/mL gudaha DMSO |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Dahab ama Jaalle-Dahab budo ah |
Daahirnimada / Habka Falanqaynta | > 97.0% (HPLC) |
Daahirnimada / Habka Falanqaynta | 96.5 ~ 103.5% (Titration dhexdhexaadinta) |
Meesha dhalaalaysa | 177.0 ~ 183.0 ℃ |
Biyaha (waxaa qoray Karl Fischer) | <0.50% |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.50% |
Wadarta wasakhda | <2.00% |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyeyaasha Daawooyinka |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
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8-Hydroxy-5-Nitroquinoline (5-Nitro-8-Quinolinol; Nitroxoline) (CAS: 4008-48-4) waa monohydroxyquinoline kaas oo kooxda hydroxy ay ku yaalliin C-8 oo leh koox nitro ah oo u gudubta C-ga 8-Hydroxy-5-Nitroquinoline waa wakiilka anti-microbial iyo anti-kansarka ee waxtarka leh.Waa wakiilka bakteeriyada kaadi-mareenka oo leh bioactivity lid ku ah noolaha garaam-positive iyo gram-negative caadi ahaan u nugul caabuqa kaadi mareenka.Nitroxoline waa antibiyootiko la xaqiijiyay in ay aad waxtar ugu leedahay la dagaallanka caabuqyada biofilm.Nitroxoline waxay u shaqeysaa iyada oo jebinaysa Fe2+ iyo Zn2+ ions oo ka soo jeeda shaxanka biofilm.8-Hydroxy-5-Nitroquinoline waxay joojin kartaa dhaqdhaqaaqa cathepsin B waxayna door ka ciyaareysaa iska caabinta buro ku jirta vivo iyo in vitro.8-Hydroxy-5-Nitroquinoline ayaa loo isticmaalay isku-darka novel CO2-soluble 8-hydroxyquinoline chelating agents.