Adenosine CAS 58-61-7 Assay 99.0% -101.0% USP Standard Factory High Nadiifin Sawirka

Adenosine CAS 58-61-7 Assay 99.0% -101.0% USP Standard Factory Nadaafad Sare

Sharaxaad Gaaban:

Magaca: Adenosine

CAS: 58-61-7

Muuqashada: Budada Crystalline White, Aan ur lahayn

Qiimaynta: 99.0% ~ 101.0% (ku salaysan qalalan)

Heerka USP35, Tayada Sare, Wax soo saarka Ganacsiga

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Email noogu soo dir

Faahfaahinta Alaabta

Alaabooyinka La Xiriira

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Sharaxaad:

Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee Adenosine (CAS: 58-61-7) oo leh tayo sare, oo la kulma heerka USP, heerka AJI97.Kiimikada Ruifu waxay keentaa taxane Nucleosides, Nucleotides, Nucleic Acids.Waxaan bixin karnaa gaarsiinta adduunka oo dhan, tiro yar iyo tiro badan oo la heli karo.Haddii aad xiisaynayso Adenosine (CAS: 58-61-7), Please contact: alvin@ruifuchem.com

Guryaha Kiimikada:

Magaca	Adenosine
La mid ah	D-Adenosine;Adenosine, Saldhig bilaash ah;Adenocard;Adenine Riboside;9-beta-D-Ribofuranosyladenine;9-β-D-Ribofuranosyladenine;6-Amino-9β-D-Ribofuranosyl-9H-Purine;6-Amino-9 (β-D-Ribofuranosyl) -9H-Purine;Adenine-9-beta-D-Ribofuranoside
Lambarka CAS	58-61-7
Heerka Saamiyada	Kaydka, Awoodda Wax-soo-saarka 500 Tan sanadkii
Qaanuunka molecular	C10H13N5O4
Miisaanka Molecular	267.25
Meesha dhalaalaysa	233.0 ~ 238.0 ℃
Xasaasi ah	Xasaasiyadda hawada
Solubility	In yar oo Biyaha ku milmaya, Ku milma Biyaha Kulul, Dhaqan ahaan Aan ku milmi karin Ethanol (96 boqolkiiba) iyo Methylene Chloride
Ku milmay biyaha kulul	Ku dhawaad Hufnaan
Kala soocidda	Nucleosides, Nucleotides, Nucleic Acids
Summada	Kiimikada Ruifu

58-61-7 Macluumaadka Badbaadada:

Bayaanka Khatarta	36/37/38	F	10-23
Bayaanada Badbaadada	24/25-36/37/39-26	TSCA	Haa
WGK Germany	2	Koodhka HS	2934993090
RTECS	AU7175000	Sunta	LD50 afka ah ee jiirka:> 20gm/kg

Tilmaamaha:

Walxaha	Heerarka Kormeerka	Natiijooyinka
Muuqashada	Budada Crystalline White, Aan ur lahayn	U hogaansama
Aqoonsiga	IR Waafaqsan Tixraaca	U hogaansama
Wareeg gaar ah [a]20/D	-68.0°～-72.0° (C=2 gudaha 5% NaOH)	-71.7°
Meesha dhalaalaysa	233.0 ~ 238.0 ℃	235.0 ~ 236.0 ℃
Aysiidh ama Alkalinity	Buuxiyay Shuruudaha	U hogaansama
Khasaare xagga qalajinta	≤0.50%	0.04%
Biraha culus	≤10pm	<10pm
Hadhaaga dabka	≤0.10%	0.08%
Xadka Ammonia	≤0.0004%	<0.0004%
Xadka chloride	≤0.007%	<0.007%
Xadka Sulfate	≤0.02%	<0.02%
Guanosin	≤0.10%	Maqnaanshaha
Wadnaha	≤0.10%	0.01%
Uridine	≤0.10%	Maqnaanshaha
Adenine	≤0.10%	Maqnaanshaha
Wadarta wasakhda	≤0.50%	0.03%
Qiimayn	99.0 ~ 101.0% (ku salaysan qalalan)	100.3%
Heerka Imtixaanka	USP35 Standard	U hogaansama
Alaabta Hoosta	Adenosine Triphosphate (ATP), Adenine, Adenylate, Adenosine Arabinose

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka.Aan ku habboonayn walxaha oksaydhaynta ee xooggan.

58-61-7 USP35 Habka Imtixaanka:

Qeexitaan
Adenosine wuxuu ka kooban yahay NLT 99.0% iyo NMT 101.0% ee C10H13N5O4, oo lagu xisaabiyo sal qallalan.
AQOONSIGA
• A. NUUugista INfrared <197K>: NMT 0.1%
ASSAY
• ADENOSINE
Tusaalaha: 200 mg oo Adenosine ah oo hore loo qalajiyey 105 ° 2h
Nidaamka Titrimetric
(Fiiri Titrimetry <541>)
Habka: Titration toos ah
Titrant: 0.1 N halkii kiiloric acid VS
Ogaanshaha barta dhamaadka: Potentiometric
Falanqaynta: Ku mil 50 mL ee glacial acetic acid iyo titrate leh 0.1 N halkii kiiloric acid VS.Xisaabi boqolkiiba Adenosine (C10H13N5O4) ee qaybta la qaaday:
Natiijadu = [(V - B) × N × F × 100]/W
V = Tusaalaha mugga titrant (mL)
B = mugga titrant maran (mL)
N= titrant caadiga ah (mEq/mL)
F= qodob u dhigma: 267.25 mg/mEq
W= miisaanka Tusaalaha (mg)
Shuruudaha aqbalaadda: 99.0% -101.0% ee salka qallalan
• NASAASOOYINKA
• Daridda hadhaaga <281>: NMT 0.1%
• Biraha culus, Habka II <231>: NMT 10 ppm
XADKA AMmooniya
Xalka Tusaalaha: Laal 0.5 g 10 ml oo biyo ah.Walaaq ilaa 30 ilbiriqsi, oo dhex mari filtar aan dhab ahayn.Ku qas sifeeyaha biyo ilaa 15 mL, oo isticmaal sifeeyaha.
Xalka caadiga ah: 0.4 µg/ml oo ammonium chloride ah oo biyo ah
Falanqaynta: Xalka Tusaalaha iyo xalka caadiga ah ku dar 0.3 mL oo ah alkaline mer curic–potassium iodide TS, dabool tuubooyinka tijaabada, una ogolow inay istaagto 5 min.
Shuruudaha aqbalaadda: Xalka Tusaalaha ma soo bandhigo midab huruud ah oo ka daran kan xalalka caadiga ah (NMT 4 ppm of ammonia).
XADKA KOloriinta
Xalka Tusaalaha: Laal 0.2 g 10 ml oo biyo ah.Walaaq ilaa 30 ilbiriqsi, dhex mari shaandhooyin aan dhab ahayn, oo isticmaal sifeeyaha.
Xalka caadiga ah: 2.3 µg/ml oo ah sodium chloride oo biyo ah
Falanqaynta: Xalka Tusaalaha iyo 10 mL ee xalalka caadiga ah ku dar 1 ml oo nitric acid ah iyo 1 ml oo nitrate qalin ah TS, oo ku qas xal kasta biyo ilaa 40 ml.U ogolow xalalku inay istaagaan 5 daqiiqo, oo laga ilaaliyo iftiinka.
Shuruudaha aqbalaadda: Marka lagu eego asalka mugdiga ah, muunad xalku maaha mid ka qallafsan xalka caadiga ah (NMT 0.007% chloride).
XADKA SULFATE
Xalka Tusaalaha: Laali 0.75 g 15 ml oo biyo ah.Walaaq ilaa 30 ilbiriqsi, dhex mari shaandhooyin aan dhab ahayn, oo isticmaal sifeeyaha.
Xalka caadiga ah: Ku dar 0.15 ml oo 0.020 N sulfuric acid ilaa 15 ml oo biyo ah.
Falanqaynta: Xalka Tusaalaha iyo xalalka caadiga ah ku dar 2 mL oo ah barium chloride TS iyo 1 mL oo ah 3 N hydrochloric acid, ku qas xal kasta oo biyo ah ilaa 30 mL, iskuna qas.U ogolow xalalku inay istaagaan 5 daqiiqo.
Shuruudaha aqbalaadda: Xalka Muunaduhu maaha mid turbid ka badan kan caadiga ah (NMT 0.02% sulfate).
• wasakhda noolaha ah
Xalka A: 6.8 g/L ee potassium hydrogen sulfate iyo 3.4g/L ee tetrabutylammonium hydrogen sulfate ee biyaha.Ku hagaaji 2 N potassium hydroxide una beddel pH ah 6.5.
Xalka B: 0.1 g/L oo ah xal sodium azide ah
Marxaladda mobilada: Xalka A iyo Xalka B (60:40)
Xalka ku habboonaanta nidaamka: 0.2 mg/mL mid kasta oo Adenosine ah iyo inosine ee wajiga mobilada
Xalka muunada: 1.0 mg/ml ee Adenosine ee wajiga mobaylka
Nidaamka Chromatographic
(Fiiri Chromatography <621>, Habboonaanta Nidaamka.)
Habka: LC
Baaraha: UV 254 nm
Tiirka: 4.6-mm × 25-cm;5-µm xirmo L1
Heerka socodka: 1.5 ml/min
Cabbirka duritaanka: 20 µL
Ku habboonaanta nidaamka
Tusaalooyinka: Xalka ku habboonaanta nidaamka
Shuruudaha ku habboonaanta
Xallinta: NLT 9.0 inta u dhaxaysa adenosine iyo inosine
Qodobka dabada: NMT 2.5
Qiyaasta heerka qaraabada: NMT 2.0%
[Xusuusin-Chromatograph xalka Tusaalaha, oo ku hagaaji wakhtiga socodsiinta ugu yaraan laba jeer wakhtiga haynta ee ugu sarreysa.]
Falanqaynta
Tusaalaha: Tusaale xal
Xisaabi boqolkiiba wasakh kasta ee qaybta Adenosine ee la qaatay:
Natiijadu = (rU/rT) × 100
rU = jawaabta ugu sarreysa ee wasakh kasta oo ka timaadda xalka Tusaalaha
rT = wadarta dhammaan jawaabaha dhammaan meelaha ugu sarreeya ee xalka Tusaalaha
Shuruudaha aqbalaadda
Nijaasta shakhsi ahaaneed: NMT 0.1% mid kasta oo ah guanosine, inosine, iyo uridine, iyo NMT 0.2% ee adenine
Wadarta wasakhda: NMT 0.5%
IMTIXAANO GAAR AH
• Kala duwanaanta AMA heerkulka <741>: 233°-238°
• Wareegga indhaha, Wareega Gaarka ah <781S>: -68° ilaa -72°
Xalka tijaabada: 20 mg / mL ee xalka sodium hydroxide (1 ee 20), oo lagu go'aamiyay muunad hore loo qalajiyey 105 ° 2h
AACIDITY AMA ALKALINITY: Jooji 1 g 20 mL oo biyo ah oo aan lahayn kaarboon laba ogsaydh.Walaaq ilaa 30 ilbiriqsi, oo dhex mari filtar aan dhab ahayn.Mid kasta oo ka mid ah labada qaybood ee 10-mL ee shaandhada ku dar 0.1mL oo bromocresol ah TS.
Shuruudaha aqbalaadda: NMT 0.3 mL oo ah 0.01 N sodium hydroxide ayaa loo baahan yahay si loo soo saaro midab buluug-violet ah hal qayb.NMT 0.1 mL oo ah 0.01 N hydrochloric acid ayaa loo baahan yahay si loo soo saaro midab huruud ah qaybta kale.
• QALABKA QASAARAN <731>: Ku qalaji muunad 105 ℃ 2 saac: waxay luminaysaa NMT 0.5% miisaankeeda.
SHURUUD DHEERAAD AH
Baakadaha iyo Kaydinta: Ku kaydi weelasha cidhiidhiga ah, kuwa iftiinka u adkaysta, kuna kaydi heerkulka qolka kontaroolan.
• HEERARKA Tixraaca USP <11>
USP Adenosine RS

Faa'iidooyinka

FAQ:

Codsiga:

Shaqada iyo Codsiga Adenosine (CAS: 58-61-7)
1. Adenosine waa borotiinada kinase activators.Hagaajinta hypoxia myocardial, balaadhinta halbowlaha wadnaha, kordhinta qanjidhada myocardial, korodhka wax soo saarka wadnaha iyo saamaynta kale ee angina pectoris, daawaynta wadna xanuunka myocardial ba'an, laakiin doorkeeda ilaalinta waqti gaaban.Waxaa loo isticmaalaa in lagu nafiso angina iyo wadnaxanuun myocardial ba'an iyo cudurro kale.Adenosine wuxuu door physiological ah ka ciyaaraa habka wadnaha iyo xididada iyo habab badan oo jirka ah.
2. Adenosine waxaa loo isticmaalaa isku-dhafka adenosine triphosphate, adenosine (ATP), adenine, adenosine, dhexdhexaadiyaha muhiimka ah ee vidarabine.Adenosine oo inta badan loo isticmaalo warshadaha dawooyinka ee soo saarista adenosine;adenosine triphosphate;coenzyme iyo taxanihiisa alaabooyinka sida adenosine phosphate cyclic iyo dawooyinka kale sida alaabta ugu muhiimsan.
3. Adenosine wuxuu door muhiim ah ka ciyaaraa biochemistry, oo ay ku jiraan adenosine triphosphate (ATP) ama adeno-bisphosphate (ADP) qaabka wareejinta tamarta, ama adenosine monophosphate (cAMP) wareegga wareegga ah ee gudbinta calaamadaha iyo wixii la mid ah.Intaa waxaa dheer, adenosine waa neurotransmitter xannibaad ah (neurotransmitter xannibaya), waxay kor u qaadi kartaa hurdada.
4. Adenosine waa amino acid.Daraasaduhu waxay muujinayaan awoodaha ka-hortagga laalaabka iyo maqaarka.Inkasta oo wax yar laga qoray faa'iidada maqaarka tooska ah, adenosine wuxuu door muhiim ah ka ciyaara hababka biochemical.Sida adenosine triphosphate (ATP) iyo adenosine diphosphate (ADP), waxay ku lug leedahay wareejinta tamarta, iyo sida adenosine monophosphate (cAMP) wareegga wareegga.
5. Adenosine waa daawada arrhythmic ka ah oo u beddesha paroxysmal supraventricular tachycardia una beddelo laxanka sinus.Waxa loo isticmaalaa supraventricular arrhythmias ee la xidhiidha atrioventricular.