Anastrozole CAS 120511-73-1 Tayada Sare ee Warshada API

Sharaxaad Gaaban:

Magaca: Anastrozole

CAS: 120511-73-1

Muuqashada: Caddaan ilaa-cad-cad budada crystalline

Qiimaynta: 98.0% ~ 102.0%

AnastrozoleDaawaynta Kansarka Naasaha

API Tayada Sare, Wax soo saarka Ganacsiga

Inquiry: alvin@ruifuchem.com


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Sharaxaad:

Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca Kiimikada: Anastrozole
CAS: 120511-73-1

Guryaha Kiimikada:

Magaca Anastrozole
La mid ah Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl) -1,3-benzenediacetonitrile
Lambarka CAS 120511-73-1
Lambarka CAT RF-API74
Heerka Saamiyada Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram
Qaanuunka molecular C17H19N5
Miisaanka Molecular 293.37
Solubility Ku milmay DMSO iyo ethanol
Summada Kiimikada Ruifu

 

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Budada Crystalline ee Caddaan iyo Off-White
Aqoonsiga A IR/MS Waafaqsan heerka tixraaca
Aqoonsiga B HPLC iyo qaabka ugu sarreeya: Ku habboon tixraaca
Meesha dhalaalaysa 81.0 ~ 84.0 ℃
Waxyaalaha biyaha (waxaa qoray KF) ≤0.30%
Hadhaaga dabka ≤0.10%
Khasaare xagga qalajinta ≤0.50%
Biraha culus ≤10pm
Walxaha laxidhiidha
Xumaanta A ≤0.10%
Xumaanta B ≤0.20%
Xumaanta C ≤0.20%
Xumaanta D ≤0.10%
Xumaanta E ≤0.10%
Xumaan Kale Oo Keliya ≤0.10%
Wadarta wasakhda ≤0.50%
Xalalka Haraaga ah
Cyclohexane ≤0.30%
Ethyl acetate ≤0.50%
Qiimayn 98.0% ~ 102.0% (ku salaysan qalalan)
Nolosha shelf 24 bilood
Heerka Imtixaanka Heerka Ganacsiga;USPharmacopoeia (USP) Heerka
Isticmaalka Daawaynta Kansarka Naasaha

Xidhmada & Kaydinta:

Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.

Faa'iidooyinka:

1

FAQ:

Codsiga:

Anastrozole (CAS 120511-73-1), waa non-steroidal, jiilka saddexaad achiral triazole derivative suuqay sida ARIMIDEX® by AstraZeneca Pharmaceuticals LP1.Waa mid ka mid ah jiilka saddexaad ee aromatase inhibitor kaas oo ah mid aad u tartan badan oo xakameynaya aromatase, sidaas darteed xannibaya beddelka testosterone ee estradiol iyo androstenedione galay estrone.Joojinta enzyme aromatase waxay si gaar ah u dhacdaa iyada oo loo marayo tartanka tartanka aromatase ee kooxda hemegroup ee cytochrome P450, hoos u dhigista biosynthesis estrogen ee unugyada durugsan ee jirka iyo naaska.

Anastrozole waa daaweyn guud oo si wanaagsan loo dulqaatay oo loogu talagalay kansarka naasaha marxaladda hore.Sida kuwa kale ee aromatase inhibitors, saamaynta xun ee ugu muhiimsan waxay ahayd khatarta sii kordheysa ee jabka lafaha, taas oo loogu talagalay anastrozole waxay ku xaddidnayd muddada daaweynta.Waxay si gaar ah u leedahay sun khafiif ah marka la barbar dhigo kiimoterabiga;si kastaba ha ahaatee, waxaa la ogaaday in bukaanno badan oo lagu daaweeyay anastrozole ay ka cawdeen calaamadaha wadajirka ah intii la filayay, gaar ahaan qallafsanaanta dhijitaalka ah ee la mid ah kan rheumatoid arthritis-ka.Qaar ka mid ah tijaabooyinka bukaan-socodka ee anastrozole ee haweenka postmenopausal ee qaba kansarka naasaha ee Yurub iyo Maraykanka ayaa soo sheegay xanuunada muruqyada sida dhacdooyinka xun.Anastrozole (Arimidex®) waa inhibitor aromatase ah oo lagu ansixiyey Midowga Yurub, Maraykanka iyo dalalka kale ee adduunka oo dhan si loogu isticmaalo daawaynta adjuvant ee haweenka postmenopausal ee leh marxalad hore, hormoon receptor-hormoon kansarka naasaha.Waxa kale oo laga oggolaaday Midowga Yurub iyo waddamo kale oo adduunka ah sii wadida daawaynta adjuvant ee haweenka hore u lahaa 2-3 sano ee daawaynta tamoxifen adjuvant ee kansarka naasaha.

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