Aripiprazole Dhexdhexaadiyaha CAS 129722-34-5 daahirnimo>98.0% (HPLC)
Soo saaraha Dhexdhexaadiyaha Aripiprazole oo leh daahir sare
Aripiprazole API CAS 129722-12-9
1- (2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
Magaca Kiimikada | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone |
La mid ah | 7- (4-Bromobutoxy) -3,4-Dihydroquinolin-2 (1H) -hal;7- (4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7- (4-Bromobutoxy) -2 (1H) -Quinolinone;Aripiprazole wasakhda 3 |
Lambarka CAS | 129722-34-5 |
Lambarka CAT | RF-PI2269 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C13H16BrNO2 |
Miisaanka Molecular | 298.18 |
Cufnaanta | 1.383 g/cm3 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada kristal jaalaha ah oo cad ama cirro leh |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) |
Meesha dhalaalaysa | 110.0 ~ 114.0 ℃ |
Khasaare xagga qalajinta | <1.00% |
Hadhaaga dabka | <0.50% |
Biraha culus (sida Pb) | ≤20pm |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadka Aripiprazole (CAS: 129722-12-9) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
7- (4-Bromobutoxy) -3,4-Dihydro-2 (1H) -Quinolinone (CAS: 129722-34-5) waa dhexdhexaad ka mid ah isku dhafka Aripiprazole (CAS: 129722-12-9).Badeeco xaaluf ah oo ku jirta kiniiniyada Aripiprazole.Aripiprazole (Abilify).Kan ugu cusub, longactingaripiprazole (arylpiperazine quinolinone derivative), waxay u muuqataa inay tahay qayb ka mid ah agonist ee D2 reseptors (ie, waxay kicisaa qaar ka mid ah reseptors D2 halka kuwa kalena ay xannibayaan iyadoo ku xiran meelaha ay maskaxda ku hayaan iyo uruurinta daroogada).Helitaanka bioavailability ee Aripiprazole waa qiyaastii 87%, iyadoo heerka ugu sarreeya ee dhiigga la helay 3 ilaa 5 saacadood ka dib qaadashada.Waxaa metabolized by fuuqbaxa, oxidative hydroxylation, iyo N-dealkylation, inta badan dhexdhexaadin by cagaarshow CYPs 3A4 iyo 2D6.Daawaynta schizophrenia iyo xanuunada nafsiga ah ee la xidhiidha.Dopamine D2-receptor antagonist oo door ah oo leh dopamine autoreceptor agonist.Anti-psychotic.