Atazanavir Sulfate CAS 229975-97-7 Nadiifnimada ≥99.0% API Warshada Kahortagga HIV-ga HIV-1

Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) waa nooc milix ah oo sulfate ah oo atazanavir ah kaas oo ah difaac aadka u doorta HIV-1 protease inhibitor, waa protease inhibitor ee ugu horreeya ee loo oggolaaday maamul maalinle ah.Atazanavir Sulfate waa substrate iyo horjooge CYP3A4, iyo inhibitor iyo kicin P-glycoprotein (P-gp).Atazanavir Sulfate sidoo kale waa SARS-CoV 3CLpro inhibitor leh IC50 oo ah 3.49 μM.Atazanavir Sulfate waa azapeptide iyo HIV-protease inhibitor oo loo isticmaalo daawaynta caabuqa HIV iyo AIDS marka lagu daro wakiilada kale ee ka hortagga HIV, waxaa soo saaray oo bilaabay Bristol-Myers Squibb (BMS), iyada oo hoos timaada shatiga aduunka Novartis, daawaynta caabuqa HIV.Atazanavir waxa laga bilaabay Maraykanka sidii Reyataz™ bishii Luulyo 2003. Ka hortagga fayraska.Atazanavir wuxuu muujiyay inuu guud ahaan ka awood badan yahay shanta hadda la ansixiyay ee HIV-1 protease inhibitors.Atazanavir waxay si xushmad leh u joojisaa habka fayraska-gaar ah ee fayraska Gag iyo Gag-Pol polyproteins ee unugyada HIV-1 ee qaba HIV-1 iyadoo lagu xirayo goobta firfircoon ee HIV-1 protease, sidaas darteed ka hortagga sameynta virions baaluq.Atazanavir ma aha mid ka hortag ah HIV-2.