Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Warshada
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee Biotin (Vitamin H) (CAS: 58-85-5) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibka Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Biotin |
| La mid ah | D-Biotin;D (+)-Biotin;Vitamin H;Bios II;Vitamin B7;Coenzyme R;Biotinum |
| Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
| Lambarka CAS | 58-85-5 |
| Qaanuunka molecular | C10H16N2O3S |
| Miisaanka Molecular | 244.31 g/mol |
| Meesha dhalaalaysa | 231.0 ~ 233.0 ℃ (lit.) |
| Biyuhu milmayn | In yar oo Biyo ah |
| Ku milmi kara 0.1mol/L NaOH | Ku dhawaad Hufnaan |
| Solubility | Waxoogaa Ku milma Khamriga, Chloroform, Eter |
| COA & MSDS | La heli karo |
| Asal ahaan | Shanghai, Shiinaha |
| Summada | Kiimikada Ruifu |
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | Caddaan ama ku dhawaad cad budada crystalline | Budada Crystalline White |
| Aqoonsiga | IR oo ku habboon tixraaca IR Spectrum | U hogaansama |
| Waqtiga Haynta | Waa inuu la mid yahay kan RS-ga | U hogaansama |
| Wareeg gaar ah [a]20/D | +89.0° ilaa +93.0° (C=2 gudaha 0.1 M NaOH) | +90.8° |
| Qiimayn | 97.5 ~ 100.5% | 99.8% |
| Khasaare xagga qalajinta | <0.50% | 0.05% |
| Walxaha laxidhiidha | ||
| Xumaanta Shaqsiga ah | <1.00% | U hogaansama |
| Wadarta wasakhda | <2.00% | U hogaansama |
| Xalalka Haraaga ah | ||
| Benzene | <2pm | <0.2pm |
| Toluene | <100pm | <10pm |
| DMSO | <5000pm | <500pm |
| Tijaabada Microbial | ||
| Wadarta tirada hawada ee la hirgalin karo | ≤1000cfu/g | U hogaansama |
| Wadarta khamiirka iyo caaryada | ≤100cfu/g | U hogaansama |
| Escherichia Coli | ND/1g | / |
| Staphylococcus Aureus | ND/1g | / |
| Pseudomonas Aeruginosa | ND/1g | / |
| Enterobacteria | ND/1g | / |
| Noocyada Salmonella | ND/10g | / |
| Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
Xidhmada:Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi qabow, qalalan (2 ~ 8 ℃) iyo bakhaar hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Qeexitaan Falanqaynta Biotin waxay ka kooban tahay NLT 97.5% iyo NMT 100.5% ee Biotin (C10H16N2O3S).
AQOONSIGA
• A. NUUXA NUUXDA AH <197K>
B. Waxay buuxinaysaa shuruudaha Imtixaannada Gaarka ah ee Wareegga Aragga, Wareegga Gaarka ah <781S>.
C. Wakhtiga haynta ee ugu sarraysa ee xal muunadku waxay u dhigantaa kan xalalka caadiga ah, sida lagu helay Assay.
ASSAY
HABKA
Xalka kaydinta: Ku mil 1 g oo sodium perchlorate monohydrate ah 500 ml oo biyo ah, ku dar 1 ml oo ah fosfooraska, oo ku mil biyo ilaa 1000 ml
Marxaladda mobilada: Acetonitrile iyo xalalka Buffer (8.5: 91.5)
Biyo: Acetonitrile iyo biyo (1:4)
Xalka caadiga ah: 0.1 mg/mL ee USP Biotin RS ee dareeraha.Sonicate haddii loo baahdo si ay u milaan
Xalka muunada: 0.1 mg/mL of Biotin in Diluent.Sonicate haddii loo baahdo si ay u milaan.
Nidaamka Chromatographic
(Fiiri Chromatography <621>, Habboonaanta Nidaamka.)
Habka: LC
Baaraha: UV 200 nm
Tiirka: 4.6-mm × 15-cm;3-µm xirmo L7
Heerka socodka: 1.2 ml/min
Cabbirka duritaanka: 50 µL
Ku habboonaanta nidaamka
Tusaale: Xalka caadiga ah
Shuruudaha ku habboonaanta
Qodobka dabada: NMT 1.5
Qiyaasta heerka qaraabada: NMT 2.0% ee irbado soo noqnoqda
Falanqaynta
Tusaalooyinka: Xalka caadiga ah iyo xalalka muunada
Xisaabi boqolkiiba Biotin (C10H16N2O3S) ee qaybta Biotin ee la qaatay:
Natiijadu = (rU/rS) × (CS/CU) × 100
rU = jawaabta ugu sarreysa ee xalka Tusaalaha
rS = jawaabta ugu sarreysa ee xalalka caadiga ah
CS = diiradda USP Biotin RS ee xalka caadiga ah (mg/mL)
CU = fiirsashada Biotin ee xalka muunada (mg/mL)
Shuruudaha aqbalaadda: 97.5% -100.5%
XANUUNKA
• KALA XIRIIR
Xalka Buffer, Marxaladda Mobilka, Diluent, Xalka caadiga ah, Xalka Tusaalaha, Nidaamka Chromatographic iyo Habboonaanta Nidaamka: U wad sida lagu faray Assay.
Falanqaynta
Tusaalaha: Tusaale xal
Cabir jawaabaha ugu sarreeya ee xalka Tusaalaha.
Xisaabi boqolkiiba wasakh kasta ee qaybta Biotin ee la qaatay:
Natiijadu = (rU/rT) × 100
rU = jawaabta ugu sarreysa ee wasakh kasta oo ka timaadda xalka Tusaalaha
rT = wadarta jawaabaha ugu sarreeya ee dhammaan meelaha ugu sarreeya ee xalka Tusaalaha
Shuruudaha aqbalaadda
Nijaasnimada shaqsiga ah: NMT 1.0%
Wadarta wasakhda: NMT 2.0%
IMTIXAANO GAAR AH
• Wareegga indhaha, Wareegga Gaarka ah <781S>
Xalka muunada: 20 mg/mL ee 0.1 N sodium hydroxide
Shuruudaha aqbalaadda: +89° ilaa +93°
SHURUUD DHEERAAD AH
Baakadaha iyo Kaydinta: Ku kaydi weelal cidhiidhi ah.
• HEERARKA Tixraaca USP <11>
USP Biotin RS
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
Suuqyada Waaweyn?Iibiya suuqa gudaha, Waqooyiga Ameerika, Yurub, Hindiya, Kuuriya, Jabbaan, Australia, iwm.
Faa'iidooyinka?Tayada sare, qiimo jaban, adeegyo xirfadeed iyo taageero farsamo, gaarsiin degdeg ah.
TayadaHubinta?Nidaamka xakamaynta tayada adag.Qalabka xirfadlayaasha ah ee falanqaynta waxaa ka mid ah NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Imtixaanka xadka Microbial, iwm.
Tusaalooyinka?Badeecadaha intooda badani waxay bixiyaan muunado bilaash ah oo loogu talagalay qiimeynta tayada, kharashka dhoofinta waa in ay bixiyaan macaamiisha.
Hantidhawrka Warshada?Hantidhawrka warshada soo dhawoow.Fadlan horay u sii ballan.
MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
Waqtiga dirida? Haddii ay ku jirto kaydka, dammaanad bixinta saddex maalmood ah.
Gaadiidka?By Express (FedEx, DHL), hawada, badda.
Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
Isku-dhafka gaarka ah?Waxay ku siin kartaa adeegyada isku-dhafka gaarka ah si ay ugu habboonaato baahiyahaaga cilmi-baarista.
Shuruudaha Lacag-bixinta?Qaansheegga Proforma ayaa marka hore la soo diri doonaa ka dib marka la xaqiijiyo dalabka, oo lagu soo lifaaqay macluumaadka bangigayaga.Lacag bixinta T/T (Telex Transfer), PayPal, Western Union, iwm.
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Xeerarka Khatarta R20/21/22 - Waxyeelo u leh neefsashada, taabashada maqaarka iyo haddii la liqo.
R36/37/38 - Waxay ka xanaajisaa indhaha, habdhiska neefsiga iyo maqaarka.
Sharaxaada Badbaadada S24/25 - Ka fogow taabashada maqaarka iyo indhaha.
S36 - Xidho dhar ilaalin ku habboon.
S26 - Haddii ay dhacdo in indhaha la taabto, isla markiiba ku raaci biyo badan oo raadso talo caafimaad.
WGK Germany 1
RTECS XJ9088200
FLUKA BRAND F CODES 8
TSCA Haa
HS code 2936290000
Sunta LD50 ee afka Bakaylaha:> 2000 mg/kg
Biotin (Vitamin H; Vitamin B7) (CAS: 58-85-5)
Biotin waa fiitamiin biyo ku milma oo siddeed nooc ah, biotin.Waa coenzyme - ama caawiye ensaymes - oo loo isticmaalo falcelinta dheef-shiid kiimikaadka badan ee jirka.Dchemicalbook-biotin waxay ku lug leedahay dheef-shiid kiimikaadka dufanka iyo borotiinka, ka caawinta inay cuntada u beddesho gulukoos, taasoo jidhku u isticmaali karo tamar ahaan.Waxa kale oo ay muhiim u tahay ilaalinta maqaarka, timaha iyo xuubabka.
Ku darsiga quudinta, Biotin waxaa inta badan loo isticmaalaa digaagga iyo beeridda quudinta.Caadi ahaan jajabka tirada hore ee la isku daray waa 1%-2%.
Biotin waa kab nafaqo.Marka loo eego xeerarka Shiinaha GB2760-90, waxa loo isticmaali karaa warshad ahaan cunto ahaan gargaar farsamayneed.Waxay leedahay hawlo nafsiyeed si looga hortago cudurrada maqaarka iyo kor u qaadida dheef-shiid kiimikaadka iyo wixii la mid ah.
Biotin waa karboksylase coenzyme, oo ku lug leh falcelinta karboksiyada badan, waana koenzyme muhiim u ah dheef-shiid kiimikaadka sonkorta, borotiinka iyo baruurta.
Biotin waxa loo isticmaalaa xoojiye cunto ahaan.Biotin waxaa loo isticmaalaa cuntada dhallaanka oo dhan 0.1 ~ 0.4mg/kg, ee dareeraha la cabbo 0.02 ~ 0.08mg/kg.
Biotin waxaa loo isticmaali karaa calaamadaynta borotiinnada, antigens, unugyada difaaca jirka, asiidhka nucleic (DNA, RNA) iyo wixii la mid ah.
Biotin waxay ka dhigi kartaa timo dabacsan, waxay ka hortagtaa luminta timaha hore waxayna wanaajisaa caabbinta dabiiciga ah ee maqaarka.Waxa kale oo ay leedahay waxtar gaar ah oo ka hortagga laalaabka.Waxay kor u qaadi kartaa qaab dhismeedka guud ee maqaarka, kordhinta dabacsanaanta ciddiyaha, hagaajinta qaab dhismeedka ciddiyaha jilicsan waxayna ka dhigi kartaa ciddiyaha si aad u fiican oo siman iyada oo kor u qaadeysa isku-dhafka lipids.
Maqnaanshaha biotin wuxuu keeni karaa dermatitis, atrophic glossitis, hyperesthesia, myalgia, malaise, anorexia, iyo dhiig-yaraan fudud, calaamaduhuna waxay baaba'aan marka la kordhiyo biotin.Saamaynta ugu badan ee ay leedahay waa dillaaca finanka cystic.Laakiin dadka intooda badan, xitaa isticmaalka xad-dhaafka ah ee fitamiinkan ma keeno saameyn xun.Si kastaba ha ahaatee, haweenka uurka leh waa in aanay qaadan biotin sababtoo ah khatarta dhicin.
Sunta Biotin waxay u muuqataa inay hoosayso, daaweynta seborrheic dermatitis oo leh qiyaaso badan oo Biotin ah ma muujinin dheef-shiid kiimikaadka borotiinka ee aan caadiga ahayn ama khaladaadka hidde-socodka iyo cilladaha kale ee dheef-shiid kiimikaadka.Tijaabooyinka xayawaanku waxay kaloo muujiyeen sunta Biotin yar.
