Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Nadiifinta ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Dhexdhexaad
Bixinta Sitagliptin Phosphate Monohydrate Dhexdhexaadiyaha La Xiriira:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Fosfate Monohydrate Dhexdhexaad CAS 486460-21-3
| Magaca Kiimikada | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
| La mid ah | (R)-Sitagliptin N-Boc-Acid wasakh |
| Lambarka CAS | 486460-00-8 |
| Lambarka CAT | RF-PI1192 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C15H18F3NO4 |
| Miisaanka Molecular | 333.31 |
| Meesha dhalaalaysa | 136.0 ~ 138.0 ℃ |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ilaa budo cad-cad |
| Aqoonsiga HPLC | Waqtiga Haynta ee Muunadu waa mid waafaqsan Heerka Tixraaca |
| Khasaare xagga qalajinta | ≤0.50% |
| Sulfated Ash | ≤0.50% |
| Biraha culus | <20ppm |
| Isomer | ≤0.50% |
| Walxaha laxidhiidha | |
| Xumaanta A | ≤0.50% |
| Wax kasta oo kale oo aan nadiif ahayn | ≤0.50% |
| Wadarta wasakhda | ≤0.50% |
| daahirnimo | ≥99.5% (HPLC) |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Sitagliptin Fosfate Monohydrate (CAS: 654671-77-9) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Boc-(R) -3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) waa dhexdhexaad muhiim u ah diyaarinta sitagliptin.Sitagliptinphosphate waa dipeptidase-IV (DPP-4) inhibitor-kii ugu horreeyay ee ay ansixisay FDA 2006. Waxaa loo isticmaalaa daawaynta nooca II ee sonkorowga mellitus.Waxay leedahay saameyn cad oo hypoglycemic ah marka keligiis la isticmaalo ama lagu daro metformin iyo pioglitazone, waana badbaado in la qaato, si wanaagsan loo dulqaato, iyadoo leh falcelin xun.Bishii Agoosto 2009, dawada waxaa ansixiyay Midowga Yurub inay tahay dawada safka koowaad ee daaweynta nooca 2 ee sonkorowga.Ka dib 2011, hal ka dib waddamo kale ayaa ansixiyay isku darka sitagliptin phosphate iyo alfa glycosidase inhibitors ama insulin.Sitagliptin phosphate waa daawada ugu horeysa ee FDA-ansixiso dipeptidyl peptidase-IV inhibitor si loogu isticmaalo daawaynta nooca 2aad ee sonkorowga ilaa fog, iyadoo hoos timaada magaca ganacsiga Januvia.
