Brexpiprazole CAS 913611-97-9 daahirnimo>99.0% (HPLC) Warshada API
Ruifu Kiimikada Dhexdhexaadinta Brexpiprazole
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1- (1-Benzothiophen-4-yl) Piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy) quinolin-2(1H) -hal CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Magaca Kiimikada | Brexpiprazole |
La mid ah | OPC-34712;7-(4- (4- (Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H) -hal |
Lambarka CAS | 913611-97-9 |
Lambarka CAT | RF-PI1982 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C25H27N3O2S |
Miisaanka Molecular | 433.57 |
Cufnaanta | 1.245 ± 0.060 g / cm3 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ama Banaan-cad budada Crystalline |
Aqoonsiga | By IR |
RT | Marka la eego chirality waa in ay u hoggaansamaan |
Chloride | Waxay ku siinaysaa falcelin koloriin ah |
Biyo | 3.0% ~ 4.5% |
Meesha dhalaalaysa | 198.0 ~ 202.0 ℃ |
Hadhaaga dabka | <0.20% |
Biraha culus | ≤10pm |
Walxaha laxidhiidha | |
Xumaanta Shaqsiga ah | <0.50% |
Wadarta wasakhda | <1.00% |
EE | >99.0% |
Daahirnimada / Habka Falanqaynta | > 99.0% (HPLC, ku salaysan qalalan) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Brexpiprazole (CAS: 913611-97-9) waa musharrax daroogo faa'iido u leh daaweynta iyo ka hortagga cudurrada dhimirka oo ay ku jiraan cilladaha CNS.Brexpiprazole waa daawo cusub oo ka hortagta dhimirka oo u adeegta sidii serotonin ® modulator-ka firfircoonida firfircoonida waxayna muujisay waxtarka daaweynta isku dhafan ee bukaanka qaba xanuunka weyn ee niyad-jabka (MDD).Brexpiprazole waxay soo bandhigaysaa muuqaal dawooyin gaar ah, oo u dhaqma sidii qayb ka mid ah agonist ee serotonin 5-HT1A iyo dopamine D2 reseptors iyo sida antagonist buuxa ee 5-HT2A iyo noradrenaline α1B/2C reseptors, oo leh isku xirnaanta subnanomolar isku mid ah.Brexpiprazole waxaa soo saaray Otsuka iyo Lundbeck, waxaana FDA u ansixisay 2015 daawaynta schizophrenia iyo sida daaweynta isku dhafan ee niyad-jabka.Brexpiprazole waxaa si weyn loogu tixgaliyaa inuu yahay bedelka daawada Otsuka antipsychotic aripiprazole (magaca ganacsiga Abilify) kaas oo patent-kiisu dhacay Agoosto 2014.