Brigatinib CAS 1197953-54-0 daahirnimo>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee Brigatinib (AP-26113) (CAS: 1197953-54-0) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso Brigatinib,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Brigatinib |
| La mid ah | AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl) phenyl] -N2-[2-Methoxy-4-[4- (4-Methyl-1-Piperazinyl) -1-Piperidinyl] phenyl] -2,4-Pyrimidinediamine |
| Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
| Lambarka CAS | 1197953-54-0 |
| Qaanuunka molecular | C29H39ClN7O2P |
| Miisaanka Molecular | 584.09 g/mol |
| Meesha dhalaalaysa | >203 ℃ (dac.) |
| Cufnaanta | 1.31± 0.10 g/cm3 |
| COA & MSDS | La heli karo |
| Asal ahaan | Shanghai, Shiinaha |
| Summada | Kiimikada Ruifu |
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | Caddaan ilaa budo cad-cad | U hogaansama |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) | 99.26% |
| Max.Xumaanta Keliya | <1.00% | 0.25% |
| Khasaare xagga qalajinta | <1.00% | 0.27% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| 1H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
Xidhmada:Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi bakhaar qabow, engegan oo hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
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Brigatinib (AP-26113) (CAS: 1197953-54-0) waa daawaynta kansarka la beegsanayo yar-yar oo baadhiseed oo ay samaysay ARIAD Pharmaceuticals, Inc. anaplastic lymphoma kinase (ALK).Brigatinib waa agonist door ah oo ka soo horjeeda kala duwanaanta EGFR oo ka soo horjeeda qaababka mutant duurjoogta ah.Daroogadu waxay sidoo kale muujinaysaa xulashada ka dhanka ah hidda-wadaha isku dhafka ALK-EML4, kaas oo ah dhinac aasaasi ah oo wax ka beddelka parenchyma sambabada u nugul.Brigatinib waxaa loo qoraa bukaanada leh hiddo-sideyaal aan caadi ahayn oo gaar ah iyo marka kansarka sambabada unugyada aan yareyn (NSCLC) aan ka jawaabin maareynta daawooyinka kale.Brigatinib waxaa loo kala saaraa sida kinase inhibitor, kaas oo farsamadiisa falku ka kooban yahay xakamaynta ficilka borotiinnada aan caadiga ahayn ee kor u qaadaya taranka unugyada kansarka.
Brigatinib (CAS: 1197953-54-0) waxaa loo qoraa bukaanada qaba noocyo gaar ah oo NSCLC ah oo ku faafay qaybaha kala duwan ee jirka dadka horay loogu daaweeyay dawooyinka kale ee kansarka sida Crizotinib, xaaladdooduna way sii xumaatay. ama waxay muujinayaan calaamadaha ugu yar ee horumarka.Waxaa inta badan lagu hayaa baaritaan ku saabsan waxtarkeeda daaweynta kansarka sambabada unugyada aan yareyn (NSCLC) halkaasoo ALK uu ka shaqeeyo oo isbeddellada EGFP ay si joogto ah u dhacaan.
Brigatinib (AP-26113) (CAS: 1197953-54-0) waa jiilka cusub ee xannibaya tyrosine kinase, oo muujinaya waxtarka muhiimka ah ee ALK + metastatic NSCLC.Agoosto 30, 2016, FDA-da Mareykanka waxay siisay bugtinib daawaynta horumarsan iyo daawo naadir ah oo loogu talagalay ALK + NSCLC ee bukaannada soo saaray ama aan u dulqaadan karin Crizotinib, daawaynta jiilka kowaad ee ALK+NSCLC.Mudnaanta sii dib u eegista arjiga liiska oo ogow xogta codsiga in lagu soo gudbiyo si isdaba joog ah.FDA waxay ansixisay Bugtinib Abriil 28, 2017, iyadoo hoos timaada magaca ganacsiga Alunbrigtm.
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