Candesartan CAS 139481-59-7 Nadiifinta>99.0% (HPLC) Warshada
Qalabka Kiimikada ee Ruifu Candesartan Cilexetil Dhexdhexaad oo leh daahir sare
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Dhexdhexaad Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Dhexdhexaadiyaha CAS 139481-44-0
Tril Candesartan Cilexetil CAS 170791-09-0
Magaca Kiimikada | Candesartan |
La mid ah | CV-11974;2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-Carboxylic Acid;3-[[2'- (1H-Tetrazol-5-yl) biphenyl-4-yl] methyl] -2-ethoxy-3H-Benzimidazole-4-Carboxylic Acid;Candesartan M1;Candesartan Cilexetil EP Impurity G |
Lambarka CAS | 139481-59-7 |
Lambarka CAT | RF-PI1889 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C24H20N6O3 |
Miisaanka Molecular | 440.45 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Cad |
Aqoonsiga-HPLC | Waqtiga Haynta La mid ah Heerka |
Aqoonsiga-IR | La mid ah Standard |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
Meesha dhalaalaysa | 183.0 ~ 185.0 ℃ |
Khasaare xagga qalajinta | <0.50% |
Qoyaanka (KF) | <0.50% |
Hadhaaga dabka | <0.50% |
Biraha culus | <20ppm |
Xumaanta Shaqsiga ah | <1.00% (HPLC) |
Wadarta wasakhda | <1.00% (HPLC) |
Tusmada Dib-u-celinta | n20 / D 1.745 ~ 1.747 |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API;Daawaynta Dhiig-karka |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Candesartan (CAS: 139481-59-7) waa angiotensin II reseptor antagonist leh IC50 ee 0.26 nM.Bartilmaameedka: Angiotensin II Receptor candesartan waxaa loo tilmaamay daaweynta dhiig-karka.Candesartan Cilexetil waxaa markii ugu horreysay lagu ansixiyay GB bishii Apr 29, 1997, ka dib waxaa ansixiyay Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA) Juun 4, 1998, waxaana oggolaaday Hay'adda Farmashiyaha iyo Qalabka Caafimaadka ee Japan (PMDA) Maarso 12, 1999. Waxaa soo saartay AstraZeneca, ka dibna u suuqgeyn sidii Atacand by AstraZeneca ee GB iyo US, oo u suuqgeyn sidii Blopress by Takeda ee JP.Candesartan Cilexetil waa angiotensin II reseptor blocker (ARB), waxay xannibaysaa saamaynta vasoconstrictor iyo aldosterone ee angiotensin II iyadoo si xushmad leh u xannibaysa xidhitaanka angiotensin II ee receptor AT1 unugyo badan, sida muruqa siman xididdada dhiigga iyo qanjidhada adrenal.Atacand waxaa loogu talagalay daawaynta hypertension ee dadka waaweyn iyo carruurta 1 ilaa <17 sano jir, wadne hawlgabka (NYHA fasalka II-IV) oo loo isticmaalo si loo yareeyo dhimashada wadnaha iyo wadnaha oo aan shaqayn isbitaalka.