Capecitabine CAS 154361-50-9 Nadiifinta 98.0% ~ 102.0% API Tayada Sare
Qaybinta Ganacsiga ee Capecitabine Dhexdhexaadinta La Xiriira:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
| Magaca Kiimikada | Capecitabine |
| Lambarka CAS | 154361-50-9 |
| Lambarka CAT | RF-API08 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C15H22FN3O6 |
| Miisaanka Molecular | 359.35 |
| Meesha dhalaalaysa | 110.0 ~ 121.0 ℃ |
| Xaalada Maraakiibta | Heerkulka deegaanka hoostiisa |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Cad |
| Aqoonsiga | Muunadda IR Spectrum waa in ay la socotaa spectrum ee heerka tixraaca |
| Aqoonsiga | HPLC: Waqtiga haynta ee ugu sarreysa xalka muunada waa inuu u dhigmaa heerka tixraaca. |
| daahirnimo | 98.0% ~ 102.0% (oo ku salaysan anhydrous iyo dareere-free) |
| Wareegga indhaha | +96.0°~+100° |
| Qoyaanka (KF) | ≤0.30% |
| Hadhaaga dabka | ≤0.10% |
| Biraha culus | ≤20pm |
| Xumaanta La Xidhiidha A | ≤0.30% |
| Xumaanta La Xiriira B | ≤0.30% |
| Xumaanta La Xidhiidha C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Xumaanta Keliya Aan La cayimin | ≤0.10% |
| Wadarta wasakhda aan la cayimin | ≤0.50% |
| Wadarta wasakhda | ≤1.5% |
| Xalalka Hadhaaga ah (GC) | |
| Methanol | ≤3000pm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600pm |
| Ethyl acetate | ≤5000ppm |
| Toluene | ≤800pm |
| Pyridine | ≤200pm |
| Hexane | ≤290pm |
| Wadarta tirada Microbial Aerobic | ≤200cfc/g |
| Khamiirka iyo caaryada ayaa tirinaya | ≤50cfc/g |
| Heerka Imtixaanka | Pharmacopoeia ee Maraykanka (USP) |
| Isticmaalka | Kansarka Naaska Metastatic |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Capecitabine (CAS: 154361-50-9) waa nooc cusub oo daawada pyrimidine fluorinated afka ah.Capecitabine waxaa soo saartay Roche Pharmaceuticals, magaceeda ganacsina waa Xeloda.Capecitabine waxay u bedeli kartaa vivo 5-FU, anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate daroogada kaas oo bartilmaameedsada unugyada kansarka si loo xakameeyo kala qaybinta unugyada oo ay carqaladeeyaan RNA iyo borotiinka.Saameynteedu waxay si weyn ugu xiran tahay heerka muujinta TP enzyme ee unugyada neoplastic iyo enzyme DPD ee muujinta vivo.Waxay ku habboon tahay daaweyn dheeraad ah oo loogu talagalay bukaannada kansarka naasaha ee aasaasiga ah ama dheef-shiid kiimikaadka kuwaas oo aan ka jawaabin antibiyootiga paclitaxel ama anthracycline.Daawada ka hortagga kansarka, waxaa inta badan loo isticmaalaa in lagu daweeyo kansarka naasaha hoose ama metastatic, iyo sidoo kale daawaynta kansarka sambabada unugyada aan yareyn, kansarka ganaca, kansarka kaadiheysta, kansarka malawadka, kansarka mindhicirka, kansarka caloosha, iyo burooyinka kale ee adag. .
