Captopril CAS 62571-86-2 API Warshada USP Tayada Sare ee Ka-hortagga Dhiig-karka
Soo saaraha soo saaraha oo leh nadiif sare iyo tayo xasilan
Magaca Kiimikada: Captopril
CAS: 62571-86-2
Angiotensin-beddelka Enzyme (ACE) ee firfircoon ee ka hortagga dhiig-karka
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Captopril |
La mid ah | (S)-(-)-1- (3-Mercapto-2-methyl-1-oxopropyl) -L-proline;(S)-(-)-1- (3-Mercapto-2-methylpropionyl) -L-proline |
Lambarka CAS | 62571-86-2 |
Lambarka CAT | RF-API89 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C9H15NO3S |
Miisaanka Molecular | 217.29 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Crystalline ee Caddaan iyo Off-White |
Qiimayn | 98.0% ~ 102.0% (oo ku salaysan qalalan) |
Meesha dhalaalaysa | 104.0 ~ 110.0 ℃ |
Wareegga indhaha ee gaarka ah | -125.0° ilaa -134.0° |
Aysiidhka | 7.0-8.0 |
Khasaare xagga qalajinta | ≤1.0% |
Hadhaaga dabka | ≤0.10% |
Biraha culus | ≤20pm |
Walxaha laxidhiidha | |
Captopril Disulfide | ≤1.0% |
Xumaanta Keliya Aan La Aqoon | ≤0.20% |
Wadarta wasakhda | ≤0.50% |
Waxyaalaha wasakhaysan ee Dabiiciga ah | Buuxiyay Shuruudaha |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Waxa loo adeegsaday daawaynta ka hortagga dhiig-karka |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Captopril waa tan ugu badan ee la baaro angiotensin-converting enzyme (ACE) horjoogayaasha loo soo jeediyay sida daawada dhiig-karka.Waxay ka hortagtaa angiotensin-converting enzyme, taas oo xakamaysa samaynta angiotensin II waxayna yaraynaysaa saamaynta vasoconstricting ee xididdada halbowlaha ah iyo xididdada.Guud ahaan xiisadda xididada xididada xididada waa la yareeyaa, taasoo keenta hoos u dhaca cadaadiska halbowlaha.Captopril, iyo sidoo kale kuwa kale ee ACE inhibitors, ayaa lagu muujiyey daawaynta hypertension, wadne-xannuunnada wadnaha, cillad ventricular bidix ka dib wadnaxanuun myocardial, iyo sonkorowga nephropathy.Daawaynta dhiig-karka lagama maarmaanka ah, captopril waxaa loo tixgeliyaa daawaynta dookha koowaad, kaligeed ama lagu daro thiazide diuretic.Hoos u dhaca cadaadiska dhiigga ayaa ugu horrayn loo nisbeeyaa hoos u dhaca wadarta iska caabbinta durugsan ama culayska dambe.Faa'iidada isku-darka daaweynta captopril iyo diuretic thiazide ee caadiga ah ayaa ah in hypokalemia-ku keeno thiazide la yareeyo joogitaanka xannibaadda ACE, sababtoo ah hoos u dhac muuqda ee angiotensin II-ku-sii-deynta aldosterone.