Lesinurad Dhexdhexaadiyaha CAS 1533519-85-5 daahirnimo>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee Methyl 2-[[4- (4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio] acetate (CAS: 1533519-85-5) oo leh tayo sare, dhexe ee Lesinurad (CAS: 878672-00-5).Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibka Lesinurad Intermediates,Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Methyl 2-[4- (4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio] acetate |
| La mid ah | Lesinurad INT4;Lesinurad wasakhnimada 11;Methyl {[4- (4-Cyclopropyl-1-Naphthyl)-4H-1,2,4-Triazol-3-yl]sulfanyl}acetate |
| Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
| Lambarka CAS | 1533519-85-5 |
| Qaanuunka molecular | C18H17N3O2S |
| Miisaanka Molecular | 339.41 g/mol |
| Barta Karsan | 546.4± 60.0 ℃ |
| Cufnaanta | 1.38± 0.10 g/cm3 |
| COA & MSDS | La heli karo |
| Asal ahaan | Shanghai, Shiinaha |
| Qaybta | Dhexe ee Lesinurad (CAS: 878672-00-5) |
| Summada | Kiimikada Ruifu |
| Walxaha | Heerarka Kormeerka | Natiijooyinka |
| Muuqashada | Budo-cad-cad | Budo-cad-cad |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) | 99.6% |
| Nijaasta keliya ee ugu weyn | <0.50% | 0.2% |
| Wadarta wasakhda | <1.00% | 0.4% |
| Biyaha waxaa qoray Karl Fischer | <0.50% | 0.1% |
| Khasaare xagga qalajinta | <0.50% | 0.1% |
| Hadhaaga dabka | <0.20% | 0.1% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| 1H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
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Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi qabow, qalalan (2 ~ 8 ℃) iyo bakhaar hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
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Methyl 2-[[4- (4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio]acetate (CAS: 1533519-85-5) waxaa loo isticmaalaa dhex dhexaadinta Lesinurad (CAS: 878672-00-5).Ansixisay FDA dabayaaqadii 2015, lesinurad waa urate anion exchange transporter 1 (URAT1) inhibitor si loogu isticmaalo daawaynta gout.Ardea Biosciences, oo ah qayb ka mid ah AstraZeneca, ayaa soo saartay lesinurad si loogu isticmaalo daaweynta isku dhafan ee xanthine oxidase inhibitors ee daaweynta hyperuricemia ee la xidhiidha gout.Hannaanka ansixinta ayaa ka socda dhowr waddan oo kale oo adduunka ah, iyadoo Guddiga EMA ee Alaabooyinka Daawaynta ee Isticmaalka Aadanaha uu siinaya lesinurad ra'yi togan oo loo isticmaalo daawaynta isku-darka ah ee lagu daro xanthine oxidase inhibitors si loo daweeyo hyperuricemia.
