2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel daahirnimada dhexe>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) oo leh tayo sare, dhexdhexaad ah Perampanel (CAS: 380917-97-5).Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibka Perampanel dhexdhexaadiyaha, Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | 2-Cyanophenylboronic Acid 1,3-Propanediol Ester |
| La mid ah | 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2-(1,3,2-Dioxaborinan-2-yl) benzonitrile |
| Lambarka CAS | 172732-52-4 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C10H10BNO2 |
| Miisaanka Molecular | 187.01 |
| Meesha dhalaalaysa | 46.0 ~ 51.0 ℃ (Iftiin) |
| Cufnaanta | 1.13±0.10 g/cm3 |
| Solubility | Ku milma Methanol |
| Xasilooni | Hygroscopic |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ilaa qafiif ah budada jaalaha ah ilaa Crystal |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
| Khasaare xagga qalajinta | <0.50% |
| Hadhaaga dabka | <0.20% |
| Xumaanta Keliya | <0.50% |
| Wadarta wasakhda | <1.00% |
| Biraha culus (sida Pb) | <20ppm |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | Dhexdhexaadiyaha Perampanel (CAS: 380917-97-5) |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Calaamadaha halista Xi - xanaaq badan
Xeerarka Khatarta
R20/21/22 - Waxyeelo xagga neefsashada, taabashada maqaarka iyo haddii la liqo.
R36/37/38 - Waxay ka xanaajisaa indhaha, habdhiska neefsiga iyo maqaarka.
Sharaxaada Badbaadada
S26 - Haddii ay dhacdo in indhaha la taabto, isla markiiba ku raaci biyo badan oo raadso talo caafimaad.
S36/37/39 - Xidho dhar ilaalin ku haboon, galoofyada iyo ilaalinta indhaha/wejiga.
Aqoonsiga Qaramada Midoobay 3439
WGK Germany 3
TSCA Maya
Xusuusin Khatarta Irritant
2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) waxaa loo isticmaalaa isku dhafka Perampanel (CAS: 380917-97-5), AMPA antagonist receptor.Perampanel (shati la siiyay 2012) waa jiilka saddexaad ee AED oo loo yaqaan magaca sumadda leh ee Fycompa® (Eisai, Hatfield) ee UK iyo Banzel® (Eisai, Hatfield) ee Mareykanka.Bishii Oktoobar 2012, US FDA waxay ansixisay perampanel daaweynta suuxdinta qayb ahaan bilawga ah ee bukaannada suuxdinta ee ugu yaraan 12 jir ah.Perampanel waa antagonistaha AMPA ee ugu horreeya si uu u helo oggolaanshaha FDA sida AED.Receptors AMPA glutamate ayaa ugu horreyn laga helaa neurons-ka postsynaptic ee maskaxda.Xulasho ahaan, iska soo horjeeda aan tartan lahayn ee AMPA, parampanel waxay ka hortagtaa furitaanka kanaalka ion waxayna yaraynaysaa faafinta kartida ficilka.Perampanel waxaa ansixiyay Yurub EMA iyo US FDA bilihii Luulyo iyo Oktoobar 2012 siday u kala horreeyaan, waxaa loo isticmaalaa daawaynta adjuvant ee bukaanada qaba suuxdin qaybeed oo ka weyn 12 sano oo leh ama aan lahayn suuxdin nidaameed labaad.Bishii Juun 22, 2015, Eisai ayaa ku dhawaaqday in US FDA ay ansixisay ballaarinta calaamadda Pirenparanide hydrate (Fycompa) sida daawaynta adjuvant ee suuxdinta aasaasiga ah ee tonic-clonic ee bukaannada qaba suuxdin da'doodu tahay 12 iyo wixii ka sareeya.
