CAS 177036-94-1 daahirnimo>99.0% (HPLC) API Nadaafadda Sare ee Warshada

Sharaxaad Gaaban:

CAS: 177036-94-1

Daahirsanaanta:>99.0% (HPLC)

Muuqashada: Budada cad ama Off-Cad ah

Daaweynta Dhiig-karka Halbowlaha Sambabada (PAH)

API Tayada Sare, Wax soo saarka Ganacsiga

E-Mail: alvin@ruifuchem.com


Faahfaahinta Alaabta

Alaabooyinka La Xiriira

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Sharaxaad:

Guryaha Kiimikada:

Magaca Kiimikada (S)-2-[(4,6-Dimethylpyrimidin-2-yl) oxy]-3-Methoxy-3,3-Diphenylpropionic Acid
La mid ah (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl) oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid
Lambarka CAS 177036-94-1
Heerka Saamiyada Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular C22H22N2O4
Miisaanka Molecular 378.43
Wareeg gaar ah [α]D20 +170.0° ilaa +176.0° (C=0.5, MeOH)
Meesha dhalaalaysa 172.0 ~ 178.0 ℃ (dac.)
Solubility Aad ugu milmay Methanol;Ku milmay Ethanol, Acetone;Aan ku milmin Biyaha
Summada Kiimikada Ruifu

Tilmaamaha:

Shayga Tilmaamaha
Muuqashada Budada cad ama Off-Cad
Aqoonsiga HPLC;NMR;LC-MS
Walxaha laxidhiidha  
Xumaanta Shaqsiga ah ≤0.50%
Wadarta wasakhda <1.00%
Khasaare xagga qalajinta ≤0.50%
Hadhaaga dabka ≤0.20%
Biraha culus ≤20pm
Daahirnimada / Habka Falanqaynta >99.0% (HPLC)
Heerka Imtixaanka Heerka Ganacsiga
Isticmaalka Dhexdhexaadiyeyaasha Daawooyinka

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka:

1

FAQ:

Codsiga:

(CAS: 177036-94-1) APIwaa antagonist endothelin-A (ETA) oo la xushay oo loo soo bandhigay daaweynta afka ee bukaanka qaba hypertension sambabada (PAH), si loo hagaajiyo awoodda jimicsiga iyo dib u dhigista kiliinikada.PAH waa cudur naadir ah oo ku dhaca halbowlayaasha sambabada yaryar ee lagu garto faafinta xididada iyo dib u habeynta, taasoo keentay koror sii kordhaya ee iska caabbinta sambabada sambabada iyo cadaadiska halbowlaha sambabada, iyo ugu dambeyntii, fashilka saxda ah ee saxda ah iyo dhimashada hore.Calaamadaha ugu horreeya ee PAH waxaa ka mid ah neefta oo si tartiib ah u bilaabata, daal, garaaca wadnaha, barar, iyo miyir beelid.Endothelin-1 (ET-1), vasoconstrictor awood leh iyo mitogen muruqa siman, waa qayb muhiim ah oo ka qaybqaata dardargelinta cudurka, saameyntiisana waxaa lagu dhexdhexaadiyaa iyada oo loo marayo firfircoonida ETA iyo ETB.Bishii Juun 2007, FDA waxay ogolaatay (CAS: 177036-94-1) API daawaynta hal mar ee PAH.

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