6,7-Bis (2-Methoxyethoxy) -4 (3H) -Quinazolinone CAS 179688-29-0 Erlotinib Hydrochloride Nadiif Dhexdhexaad ah>99.0% (HPLC)
Soo saaraha hormuudka ah iyo alaab-qeybiyaha Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-hal CAS 179688-29-0
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Magaca Kiimikada | 6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-kow |
La mid ah | 6,7-Bis (2-Methoxyethoxy) -4 (3H) -Quinazolinone;6,7-Bis (2-Methoxyethoxy) -3,4-Dihydroquinazolin-4-hal;6,7-Bis (2-Methoxyethoxy) -4-Hydroxyquinazoline;6,7-Bis (2-Methoxyethoxy) -4-Quinazolinol;CP-380736 |
wasakhnimo | Erlotinib wasakh A;Erlotinib Lactam wasakh |
Lambarka CAS | 179688-29-0 |
Lambarka CAT | RF2685 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C14H18N2O5 |
Miisaanka Molecular | 294.31 |
Meesha dhalaalaysa | 190.0 ilaa 194.0 ℃ |
Cufnaanta | 1.26±0.1 g/cm3 |
Xasaasi ah | Xasaasiyadda hawada |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama Off-Cad |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
Meesha dhalaalaysa | 190.0 ilaa 194.0 ℃ |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.20% |
wasakhda laxidhiidha ee HPLC | |
Xumaanta Shaqsiga ah | <0.50% |
Wadarta wasakhda | <1.00% |
Biraha culus | <10pm |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Erlotinib Hydrochloride (CAS: 183319-69-9) |
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6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-kow (CAS: 179688-29-0) waa dhexdhexaadiye Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochlorate waa molecule yar oo tyrosine kinase inhibitor ah kaas oo u dhaqma dib-u-soo-celinta unugyada koritaanka epidermal, hydrochloride of erlotinib, daawo molecular bartilmaameedsan.Maamulka Cuntada iyo Dawooyinka ee Maraykanka (FDA) ayaa ansixiyay erlotinib (Tarceva) oo lagu daray gemcitabine oo ah daawaynta safka hore ee kansarka beeryarada ee gudaha iyo metastatic.Waxaa inta badan loo isticmaalaa daawaynta safka labaad ama sadexaad ee kansarka sambabada unugyada aan unugyada yaryarayn ee maxaliga ah ama mestatic iyo sida daawaynta kansarka ganaca.Waxa loo istcimaalaa sidii tyrosine inhibitor ah oo loogu talagalay daawaynta NSCLC.Unugyada unugyada yar yar ee Erlotinib Hydrochlorate waa tyrosine kinase reseptor inhibitor kaas oo xakameynaya kororka unugyada burooyinka iyadoo la xakameynayo fosfooraska, ku xira qaybta catalytic intracellular ee tyrosine kinase ee tartanka ATP, sidaas darteed xannibaya gudbinta calaamadaha hoose iyo joojinta dhaqdhaqaaqa ku-tiirsanaanta unugyada burooyinka HER-1/EGFR.