3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Nadiif Dhexdhexaad ah>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee 3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso Lapatinib Dhexdhexaadiyeyaasha,Please contact: alvin@ruifuchem.com
Magaca Kiimikada | 3-Chloro-4-(3-Fluorobenzyloxy) aniline |
La mid ah | 3-Chloro-4-[(3-Fluorophenyl) methoxy] aniline;4- (3-Fluorobenzyloxy) -3-Chlorobenzenamine;Lapatinib Dhexdhexaadiyaha B |
Heerka Saamiyada | Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga |
Lambarka CAS | 202197-26-0 |
Qaanuunka molecular | C13H11ClFNO |
Miisaanka Molecular | 251.69 g/mol |
Meesha dhalaalaysa | 78.0 ilaa 82.0 ℃ |
Cufnaanta | 1.306 ± 0.06 g / cm3 |
COA & MSDS | La heli karo |
Tusaale | La heli karo |
Asal ahaan | Shanghai, Shiinaha |
Summada | Kiimikada Ruifu |
Walxaha | Heerarka Kormeerka | Natiijooyinka |
Muuqashada | Brown ilaa budada madow | U hogaansama |
Meesha dhalaalaysa | 78.0 ilaa 82.0 ℃ | 80.7 ℃ |
Khasaare xagga qalajinta | <1.00% | U hogaansama |
Hadhaaga dabka | <0.50% | U hogaansama |
wasakhda laxidhiidha ee HPLC | <2.00% | 0.64% |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) | 99.36% |
1H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
Codsiga | Dhexdhexaadka Lapatinib / Lapatinib Ditosylate Monohydrate |
Xidhmada:Dhalada fluorinated, bacda bireed aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi bakhaar qabow, engegan oo hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.
Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
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Khatarta Heerka 9
Kooxda Baakadaha III
3-Chloro-4- (3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) waa dhexdhexaad ka mid ah isku dhafka Lapatinib / Lapatinib Ditosylate Monohydrate.
Lapatinib waa daawo lagu beegsanayo kansarka naasaha oo ay soo saartay British GlaxoSmithKline Co. Human ErbB reseptors waxay ka tirsan yihiin nooca I tyrosine kinase (TK) receptor qoyska, oo ay ku jiraan ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), iyo ErbB4 (HER4) .ErbB-1 (EGFR) iyo ErbB-2 (HER-2) reseptors ayaa inta badan si xad dhaaf ah ama haddii kale ay beddelaan bukaanka kansarka.Reseptor factor factor koritaanka epidermal aadanaha 2 (ErbB-2, HER-2) waxaa loo yaqaanaa in uu yahay Kansarka aadanaha ee si dhow ula xiriira kansarka naasaha.Dareenkeeda sare ee kansarka naasaha ayaa inta badan saadaaliya metastasis-ka qanjidhada qanjidhada iyo kala duwanaanshaha burooyinka oo liita, oo leh saadaasha liidata.HER-2 waa mid ka mid ah unugyada bartilmaameedka loogu talagalay daawaynta gaarka ah ee kansarka naasaha.Lapatinib waxay ku dhaqmi kartaa isku mar labadaba Her-1 Her-2.Saamaynta bayooloji ee habkan ka hortagaya faafinta iyo korriinka unugyada burooyinka ayaa aad uga weyn in lagu dhaqmo hal bartilmaameed.Isku dhafka Lapatinib ee Capecitabine waxaa loo isticmaalaa in lagu daaweeyo bukaanada qaba kansarka naasaha ee sare ama metastatic oo leh xad-dhaaf ah oo ah reseptormal bini'aadamka2, oo horey loogu daaweeyay anthracyclines, paclitaxel, iyo trastuzumab.Tijaabooyin caafimaad ayaa muujiyay in Lapatinib uu sidoo kale si wax ku ool ah u daweeyo bukaannada kansarka nooca HER2 ee iska caabbinta Herceptin.