1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-hal CAS 27387-31-1 Ondansetron HCl Dihydrate Nadiifinta Dhexdhexaadka ah>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) oo leh tayo sare leh.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Please contact: alvin@ruifuchem.com
Dhexdhexaadiyeyaasha la xidhiidha ee Ondansetron Hydrochloride Dihydrate
1,3-Cyclohexanedione | CAS 504-02-9 |
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-hal | CAS 27387-31-1 |
Ondansetron Hydrochloride Dihydrate | CAS 103639-04-9 |
Magaca Kiimikada | 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-hal |
La mid ah | 1,2,3,4-Tetrahydro-9-Methylcarbazol-4-hal;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole |
Heerka Saamiyada | In Stock |
wasakhnimo | Ondansetron USP Isku dhafka C;Ondansetron EP wasakh C;Ondansetron Hydrochloride Dihydrate wasakh C |
Lambarka CAS | 27387-31-1 |
Qaanuunka molecular | C13H13NO |
Miisaanka Molecular | 199.25 g/mol |
Meesha dhalaalaysa | 199.0 ilaa 203.0 ℃ |
Cufnaanta | 1.21± 0.10 g/cm3 |
COA & MSDS | La heli karo |
Summada | Kiimikada Ruifu |
Walxaha | Heerarka Kormeerka | Natiijooyinka |
Muuqashada | Budada Crystalline ee Caddaan iyo Off-White | U hogaansama |
Meesha dhalaalaysa | 199.0 ilaa 203.0 ℃ | 200.0 ilaa 202.0 ℃ |
Xumaanta Keliya | <0.50% | U hogaansama |
Wadarta wasakhda | <1.00% | U hogaansama |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) | 99.65% |
1 H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
Gabagabo | Alaabta waa la tijaabiyay oo waafaqay qeexitaannada |
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MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
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Xeerarka Khatarta
R36/37/38 - Waxay ka xanaajisaa indhaha, habdhiska neefsiga iyo maqaarka.
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R25 - Sun haddii la liqo
Sharaxaada Badbaadada
S22 - Ha neefsan boorka.
S24/25 - Iska ilaali taabashada maqaarka iyo indhaha.
S61 - Iska ilaali in lagu sii daayo deegaanka.Tixraac tilmaamaha gaarka ah / xaashiyaha xogta badbaadada.
S45 - Haddii ay dhacdo shil ama haddii aad dareento xanuun, raadso talo caafimaad isla markiiba (tus calaamadda mar kasta oo ay suurtagal tahay.)
UN IDs UN 2811 6.1 / PGIII
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) waxaa loo istcimaalaa dhex dhexaadiyaha Ondansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Horumarinta shirkadda Glaxo ee Boqortooyada Ingiriiska, 1990 gudaha Faransiiska, suuqa Boqortooyada Ingiriiska.Alaabta ayaa ah serotonin aadka loo xushay (5-HT3) antagonist receptor antagonist, waxay joojin kartaa Lallabada ay keento kiimoterabiga iyo shucaaca matagga, oo leh awood sare iyo xulashada sare, waxay xakameyn kartaa xiidmaha yar iyo kuwa CTZ ee ay keento kicinta matagga.Waxay ku habboon tahay daawaynta matagga Lallabbo ee ay keento kiimoterabiga iyo daaweynta shucaaca, waxaana sidoo kale loo isticmaali karaa ka-hortagga iyo daawaynta Lallabada Matagga ee sababa qalliinka ka dib.
Ondansetron, granisetron iyo dolasetron waa saddex dawooyinka antiemetic sida caadiga ah loo isticmaalo rugta caafimaadka, ondansetron waa mid awood leh, la xushay oo dib loo celin karo 5-hydroxytryptamine (5-HT3) receptor blocker for Alpha 1, Alpha 2, beta 1, Beta 2 adrenergic reseptors iyo histamine H1, H2 reseptor saameyn yar ayuu leeyahay, mana laha wax saameyn liddi ku ah H reseptor, dhexe iyo durugsan dopaminergic reseptors, oo waxay joojin karaan Lallabada iyo Matagga ay keento kemotherabi iyo daaweynta shucaaca.Marka la barbar dhigo metoclopramide, Saamaynta antiemetic waxay ahayd mid xoogan mana jirin falcelin ka baxsan pyramidal.Cisplatin, cyclophosphamide, doxorubicin oo uu keeno matag ayaa soo saari kara saameyn degdeg ah oo xooggan oo ka hortagga lallabbo.Ku habboon daawaynta dawooyinka cytotoxic ee ay keento daawaynta kiimoterabiga iyo daawaynta shucaaca Lallabbo matag, laakiin sidoo kale ka hortagga iyo daawaynta matagga Lallabada ee uu keeno qaliinka.ondansetron wuxuu u shaqeeyaa sidii xarun wareejin oo u dhaxaysa dareemayaasha afferent visceral ee firfircoon ee mareenka caloosha iyo mindhicirka iyo Matagga xarumaha xudunta laf-dhabarta, taasoo keenta dhaqdhaqaaqa caloosha iyo diaphragmatic.Dawooyinka kiimoterabiga iyo daaweynta shucaaca waxay sababi karaan sii deynta 5-HT ee mindhicirka yar, iyo falcelinta matagga waxaa sababa kicinta neerfaha siilka iyada oo loo marayo soo-dhoweeyaha 5-HT3.Alaabtani waxay xannibaysaa dhacdada fal-celintan, iyada oo xannibaysa matagga uu kiciyay ficil dhexe.Habka ficilka looma aqoon Labbo Matag qaliinka ka dib.Ondansetron oo lagu daray dexamethasone waxay kor u qaadi kartaa saameynta antiemetic.