CAS 274901-16-5 daahirnimo ≥99.0% (HPLC) API
Dhexdhexaadiyaha La Xiriira Soo Saaraha:
CAS: 274901-16-5
3-Amino-1-Adamantanol CAS: 702-82-9
L-Prolinamide CAS: 7531-52-4
Boc-L-Proline CAS: 15761-39-4
(2S)-1-(Chloroacetyl)-2-Pyrrolidinecarbonitrile CAS: 207557-35-5
La mid ah | LAF-237 |
Lambarka CAS | 274901-16-5 |
Lambarka CAT | RF-API30 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C17H25N3O2 |
Miisaanka Molecular | 303.4 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Crystalline White |
Aqoonsiga | IR, HPLC: Waa in uu waafaqsan yahay heerka tixraaca |
Wareegga indhaha ee gaarka ah | -82.0° ilaa -92.0° |
Meesha dhalaalaysa | 148.0 ~ 152.0 ℃ |
Khasaare xagga qalajinta | ≤0.50% |
Hadhaaga dabka | ≤0.10% |
Biraha culus | ≤20pm |
Sulfate | ≤0.02% |
Chloride | ≤0.05% |
Xumaanta Chiral | R-Isomer wasakh ≤0.50% |
Xalalka Haraaga ah | |
Acetonitrile | ≤410pm |
Dichloromethane | ≤600pm |
Khamriga isopropyl | ≤5000ppm |
wasakhda la xidhiidha | By HPLC |
Xumaanta A | ≤0.15% |
Xumaanta B | ≤0.15% |
Xumaanta C | ≤0.20% |
Xumaanta Keliga ah ee Kale | ≤0.10% |
Wadarta wasakhda | ≤1.00% |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API, Nooca 2 Sonkorowga Mellitus (T2DM) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka
Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya API (CAS: 274901-16-5) oo leh tayo sare leh.API (CAS: 274901-16-5)waa wakiilka afka ka-hortagga hyperglycemic (daawoyinka ka-hortagga sonkorowga) ee qaybta cusub ee dipeptidyl peptidase-4 (DPP-4) inhibitor ee daroogada.Waxaa soo saaray Novartis (Novartis) Pharmaceutical Co., Ltd, waa horjooge kale oo afka laga maamulo ee Dipeptidyl peptidase-IV.Sannadkii 2008, waxaa loo oggolaaday suuqgeynta Midowga Yurub ee daawaynta nooca 2aad ee sonkorowga.API (CAS: 274901-16-5) waxay joojisaa firfircoonida GLP-1 iyo GIP ee DPP-4, taasoo u oggolaanaysa GLP-1 iyo GIP inay xoojiyaan dheecaanka insulin ee unugyada beta oo ay xakameeyaan sii deynta glucagon ee unugyada alfa-ga jasiiradaha Langerhans ee xameetida.API (CAS: 274901-16-5) ayaa la muujiyay inay yarayso hyperglycemia nooca 2 ee sonkorowga mellitus.