CAS 361440-67-7 daahirnimo>98.5% (HPLC) Warshada
Dhexdhexaadiyayaasha La Xiriira Bixinta Kiimikada Ruifu
CAS 361442-04-8
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7
Magaca Kiimikada | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester |
La mid ah | N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butyl (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate |
Lambarka CAS | 361440-67-7 |
Lambarka CAT | RF-PI1990 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C11H18N2O3 |
Miisaanka Molecular | 226.27 |
Barta Karsan | 388.9 ± 21.0 ℃ |
Cufnaanta | 1.228 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Cad |
Daahirnimada / Habka Falanqaynta | > 98.5% (HPLC) |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.20% |
Waxyeelooyinka Shaqsiga ah | <1.00% |
Wadarta wasakhda | <1.50% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha API (CAS: 361442-04-8) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) waa dhexdhexaadiye API ah (CAS: 361442). -04-8).(CAS: 361442-04-8) waa hypoglycemic afka ah (daawoyinka ka-hortagga sokorowga) ee dipeptidyl peptidase-4 (DPP-4) inhibitor fasalka daawooyinka.Horumarka hore waxaa lahaa oo kaliya Bristol-Myers Squibb;sannadkii 2007 AstraZeneca waxay ku biirtay Bristol-Myers Squibb si ay isaga kaashadaan horumarinta xaruntii ugu dambaysay oo ay iska kaashadaan suuq-geynta dawada.Bishii Juun 2008, waxaa lagu dhawaaqay in Onglyza uu noqon doono magaca ganacsiga kaas oo lagu iibin doono.API (CAS: 361442-04-8) waxaa loo isticmaalaa monotherapy ahaan ama lagu daro dawooyinka kale ee daaweynta nooca 2 ee sonkorowga.Si degdeg ah ayaa loo nuugaa ka dib marka afka laga qaato waxayna leedahay astaan-farmakookinetic oo ku habboon qaadashada hal mar maalintii.Waxay ka ciyaartaa doorka iyada oo la joojinayo hoos u dhaca GLP-l.GLP-I waa hormoonnada si dabiici ah loogu soo saaro mindhicirka kadib qaadashada cuntada.