Lapatinib Ditosylate Monohydrate CAS 388082-78-8 daahirnimo>99.0% (HPLC)
Magaca Kiimikada | Lapatinib Ditosylate Monohydrate |
La mid ah | N-[3-chloro-4-[(3-fluorophenyl) methoxy] phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine |
Lambarka CAS | 388082-78-8 |
Heerka Saamiyada | In Stock |
Qaanuunka molecular | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Miisaanka Molecular | 943.48 |
COA & MSDS | La heli karo |
Asal ahaan | Shanghai, Shiinaha |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Jaalle Jaalle ilaa Jaalle Crystalline Powder |
Daahirnimada / Habka Falanqaynta | ≥99.0% (HPLC) |
Meesha dhalaalaysa | 240.0 ~ 242.0 ℃ |
Qoyaanka (KF) | 1.9 ~ 2.4% |
Xumaanta Keliya | ≤0.50% |
Wadarta wasakhda | ≤1.00% |
Biraha culus (sida Pb) | ≤20pm |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API;Daawaynta bukaanada qaba kansarka naasaha |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) waa cusbada ditosylate eeCAS 231277-92-2, synthetic, quinazoline afka-firfircoon leh oo leh firfircoonida antineoplastic ee suurtogalka ah.Waxay dib u celisaa fosforyaalka fosforyaalka soo-dhoweynta kobaca epidermal (EGFR), ErbB2, iyo Erk-1 iyo-2 iyo AKT kinases;waxay sidoo kale joojisaa heerarka borotiinka D-cyclin ee khadadka unugyada burooyinka bini'aadamka iyo xenografts.EGFR iyo ErbB2 waxay ku lug leeyihiin koritaanka noocyada kala duwan ee burooyinka.Waxaa loo bilaabay daawaynta HER2 (ErbB2) ee kansarka naasaha ee horumarsan ama metastatic ee haweenka helay daawayn hore.Daawada waxaa helay oo ay samaysay GlaxoSmithKline.