1- (1-Boc-4-Piperidinyl)-4-Iodopyrazole CAS 877399-73-0 Purity ≥99.0% (HPLC)

Sharaxaad Gaaban:

1-(1-Boc-4-Piperidinyl)-4-Iodopyrazole

CAS: 877399-73-0

Daahirsanaanta: ≥99.0% (HPLC)

Muuqashada: Caddaan ilaa Iftiin Jaalle Adag

Idhexe ee Crizotinib (CAS: 877399-52-5)

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Faahfaahinta Alaabta

Alaabooyinka La Xiriira

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Sharaxaad:

Shanghai Ruifu Chemical Co., Ltd. waa soo saaraha ugu horreeya ee 1- (1-Boc-4-Piperidinyl) -4-Iodopyrazole (CAS: 877399-73-0) oo leh tayo sare leh, dhexdhexaad ah Crizotinib (CAS: 877399-52). -5).Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibso Dhexdhexaadiyeyaasha Crizotinib,Please contact: alvin@ruifuchem.com

Dhexdhexaadiyaha Crizotinib:

Guryaha Kiimikada:

Magaca Kiimikada 1-(1-Boc-4-Piperidinyl)-4-Iodopyrazole
La mid ah 1-Boc-4-(4-Iodo-1H-Pyrazol-1-yl) piperidine;tert-Butyl 4- (4-Iodo-1H-Pyrazol-1-yl) piperidine-1-Carboxylate;tert-Butyl 4- (4-Iodopyrazolyl) piperidinecarboxylate;Xumaanta Crizotinib 16
Heerka Saamiyada Suuqa dhexdiisa, Wax-soo-saarka Ganacsiga
Lambarka CAS 877399-73-0
Qaanuunka molecular C13H20IN3O2
Miisaanka Molecular 377.22 g/mol
Meesha dhalaalaysa 97℃
Cufnaanta 1.60±0.10 g/cm3
Xasaasi ah Iftiinka xasaasiga ah
Heerkulka Kaydinta 2 ~ 8℃, Ka ilaali Iftiinka
COA & MSDS La heli karo
Asal ahaan Shanghai, Shiinaha
Qaybta Dhexdhexaadiyaha Crizotinib (CAS: 877399-52-5)
Summada Kiimikada Ruifu

Tilmaamaha:

Walxaha Heerarka Kormeerka Natiijooyinka
Muuqashada Cadaan ilaa iftiin jaale Adag Cad Adag
Daahirnimada / Habka Falanqaynta ≥99.0% (HPLC) 99.58%
Infrared Spectrum Waafaqsan Qaab-dhismeedka U hogaansama
1 H NMR Spectrum Waafaqsan Qaab-dhismeedka U hogaansama
ESI+ waafaqsan U hogaansama
Gabagabo Alaabta waa la tijaabiyay oo waafaqay tilmaamihii la bixiyay

Xidhmada/Kaydinta/Raridda:

Xidhmada:Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi qabow, qalalan (2 ~ 8 ℃) iyo bakhaar hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
Rarida:Ku gaarsii adduunka oo dhan hawo, by FedEx/DHL Express.Bixi keenid degdeg ah oo la isku halayn karo.

Faa'iidooyinka

Awood ku filan: Tas-hiilaad ku filan iyo farsamoyaqaanno

Adeegga Xirfadlaha: Adeegga iibsashada hal joogsi

Xidhmada OEM: Xidhmada gaarka ah iyo summada ayaa diyaar ah

Gaadhida Degdega ah: Haddii kaydku ku jiro, dammaanad bixinta saddex maalmood ah

Supply xasiloon: Hayso kayd macquul ah

Taageerada Farsamada: Xalka tignoolajiyada waa la heli karaa

Adeegga Isku-dhafka Gaarka ah: Wuxuu u dhexeeyaa garaam ilaa kiilo

Tayo Sare: Waxaa la sameeyay nidaam hubinta tayada dhamaystiran

FAQ:

Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
Khibrad 15 Sano ah?Waxaan leenahay in ka badan 15 sano oo waayo-aragnimo ah oo ku saabsan soo saarista iyo dhoofinta ee tiro balaadhan oo ah dhexdhexaad ah daawooyinka tayada sare leh ama kiimikooyinka ganaax.
Suuqyada Waaweyn?Iibiya suuqa gudaha, Waqooyiga Ameerika, Yurub, Hindiya, Kuuriya, Jabbaan, Australia, iwm.
Faa'iidooyinka?Tayada sare, qiimo jaban, adeegyo xirfadeed iyo taageero farsamo, gaarsiin degdeg ah.
TayadaHubinta?Nidaamka xakamaynta tayada adag.Qalabka xirfadlayaasha ah ee falanqaynta waxaa ka mid ah NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Imtixaanka xadka Microbial, iwm.
Tusaalooyinka?Badeecadaha intooda badani waxay bixiyaan muunado bilaash ah oo loogu talagalay qiimeynta tayada, kharashka dhoofinta waa in ay bixiyaan macaamiisha.
Hantidhawrka Warshada?Hantidhawrka warshada soo dhawoow.Fadlan horay u sii ballan.
MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
Waqtiga dirida? Haddii ay ku jirto kaydka, dammaanad bixinta saddex maalmood ah.
Gaadiidka?By Express (FedEx, DHL), hawada, badda.
Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
Isku-dhafka gaarka ah?Waxay ku siin kartaa adeegyada isku-dhafka gaarka ah si ay ugu habboonaato baahiyahaaga cilmi-baarista.
Shuruudaha Lacag-bixinta?Qaansheegga Proforma ayaa marka hore la soo diri doonaa ka dib marka la xaqiijiyo dalabka, oo lagu soo lifaaqay macluumaadka bangigayaga.Lacag bixinta T/T (Telex Transfer), PayPal, Western Union, iwm.

Codsiga:

1- (1-Boc-4-Piperidinyl) -4-Iodopyrazole (CAS: 877399-73-0) oo leh tayo sare, dhexdhexaad ah Crizotinib (CAS: 877399-52-5).Crizotinib waa daawaynta la beegsanayo ee kansarka sambabada unug yar oo ay samaysay Pfizer, USA.Waxaa loo ansixiyay suuqgeynta gudaha Mareykanka Agoosto 2011 waxaana lagu qoray tilmaamaha daawaynta kansarka sambabada caalamiga ah dhamaadka sanadka sida dawada safka kowaad ee bukaanada ALK-positive ah.La-ansixiyey Crizotinib waa habka ugu horreeya ee ogaanshaha hidda-socodka iyadoo la adeegsanayo fluorescence in situ hybridization (FISH) -VSIs ALK Break Apart FISH Probe Kit, kani waa habka hadda loo isticmaalo tijaabooyinka caafimaad ee caalamiga ah si loo ogaado EML4-ALK hiddo-wadaha isku-dhafka ah ee NSCLC.Tijaabadani waxay kaa caawin doontaa in la ogaado bukaanada laga yaabo inay ka faa'iidaystaan ​​daaweynta Crizotinib.on 25, tani waa daawadii ugu horeysay ee loo isticmaalo in lagu daweeyo bukaanada qaba deegaanka horumaray ama metastatic non-small cell kansarka sanbabada (NSCLC) in anaplastic lymphoma kinase (ALK) -positive sida ay go'aamisay SFDA-ansixiyey asay.

Crizotinib (PF-02341066) Crizotinib waa c-Met awood leh iyo ALK inhibitor, qiyamka IC50 ee baaritaanka unuggu waxay ahaayeen 11 nM iyo 24 nM, siday u kala horreeyaan.Sidoo kale waa horjooge awood leh oo ROS1 ah oo leh qiime Ki ka yar 0.025 nM.Crizotinib waxay u horseedi kartaa autophagy khadadka unugyada kansarka sanbabada ee kala duwan iyadoo la joojinayo dariiqa STAT3.

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