Enzalutamide CAS 915087-33-1 daahirnimo>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. waa saaraha ugu horreeya ee Enzalutamide (CAS: 915087-33-1) oo leh tayo sare.Kiimikada Ruifu waxay bixin kartaa gaarsiinta adduunka oo dhan, qiimo tartan ah, adeeg aad u wanaagsan, tiro yar iyo tiro badan oo la heli karo.Iibka Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Enzalutamide |
| La mid ah | MDV-3100;MDV 3100;4-[3-[4-Cyano-3-(Trifluoromethyl) phenyl] -5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
| Heerka Saamiyada | Kaydka, Awoodda Wax-soo-saarka 50 kgs bishii |
| Lambarka CAS | 915087-33-1 |
| Qaanuunka molecular | C21H16F4N4O2S |
| Miisaanka Molecular | 464.44 g/mol |
| Meesha dhalaalaysa | 198.0 ~ 200.0 ℃ |
| Cufnaanta | 1.49 |
| COA & MSDS | La heli karo |
| Asal ahaan | Shanghai, Shiinaha |
| Summada | Kiimikada Ruifu |
| Walxaha | Tilmaamaha | Natiijooyinka |
| Muuqashada | Budada Adag ee Cadaan ilaa Cadaan | U hogaansama |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) | 99.57% |
| Biyaha waxaa qoray Karl Fischer | <0.50% | 0.23% |
| Hadhaaga dabka | <0.10% | 0.06% |
| Biraha culus (Pb) | ≤20pm | <10pm |
| Walxaha laxidhiidha | ||
| Max.Xumaanta Keliya | <0.50% | <0.50% |
| Wadarta wasakhda | <1.00% | 0.43% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| 1H NMR Spectrum | Waafaqsan Qaab-dhismeedka | U hogaansama |
| Gabagabo | Alaabtu waa la tijaabiyay oo waafaqday tilmaamihii la bixiyay | |
Xidhmada:Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Weelka si adag u xidh oo ku kaydi qabow, qalalan (2 ~ 8 ℃) iyo bakhaar hawo wanaagsan leh oo ka fog walxaha aan ku habboonayn.Ka ilaali iftiinka iyo qoyaanka.
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Sidee loo Iibsadaa?Fadlan la xidhiidhDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
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Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
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Enzalutamide (CAS: 915087-33-1) waa androgen-receptor (AR) antagonist oo leh IC50 ee 36 nM, kaas oo ka xannibaya androgens inay ku xidhmaan soo-dhowrka androgen-ka oo ka hortagaya isu-beddelka nukliyeerka iyo shaqaaleysiinta wada-shaqeeyaha ee isku-dhafka ligand-receptor.Enzalutamide ayaa sidoo kale la muujiyay in ay keento apoptosis unugyada burooyinka, mana lahan wax dhaqdhaqaaq ah.Enzalutamide waa musharaxa daawaynta kansarka qanjirka 'prostate' u adkaysta.Enzalutamide, waa jiilka labaad ee androgen reseptor (AR) ee xannibaadaha.Waxay awood u leedahay inay joojiso ku-xidhka androgens-ka ee AR, AR nukliyeerka tarjumaadda, iyo xiriirka AR ee DNA-da.Bishii Agoosto 2012, FDA waxay ansixisay Enzalutamide, oo ay suuq geeyeen Medivation iyo Astellas Pharma US daawaynta kansarka qanjirka 'prostate' ee metastatic castration u adkaysta (CRPC), gaar ahaan bukaannada horey u helay Docetaxel.
